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NCT04171700 · ClinicalTrials.gov registry record · Phase 2

A Study to Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes

A Phase 2 study, sponsored by pharmaand.

Terminated
Registry status
Phase 2
Development phase
83
Enrollment target

NCT04171700: Clinical Trial Phase 2 study, sponsored by pharmaand.

NCT04171700 is a Phase 2 study that was terminated before completion, run by pharmaand. The registered enrollment target is 83 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (38% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04171700, a Phase 2 study, was terminated before completion, sponsored by pharmaand.

TERMINATED
Registry status
Phase 2
Development phase
83 participants
Enrollment target

Study Summary

A Phase 2, open-label, single-arm trial to evaluate the response of rucaparib in participants with various solid tumors and with deleterious mutations in Homologous Recombination Repair (HRR) genes.

Primary Outcome

Best overall response rate as assessed by the investigator by RECIST v1.1 (or by RECIST v1.1 and PCWG3 in participants with advanced prostate cancer).

Interventions

  • DRUG Rucaparib

Trial Details

FieldValue
Enrollment Target 83 participants
Start Date 2020-01-16
Est. Completion 2022-07-15
Phase Phase 2
pharmaand

15 total trials

Why NCT04171700 stopped before completion

NCT04171700 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 83 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (38% lower).

The record links to 0 conditions, and to 1 intervention - of which Rucaparib is the first listed.

NCT04171700 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04171700 about?

NCT04171700 is a clinical study titled "A Study to Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes". A Phase 2, open-label, single-arm trial to evaluate the response of rucaparib in participants with various solid tumors and with deleterious mutations in Homologous Recombination Repair (HRR) genes.

What is the current status of trial NCT04171700?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 83 participants. The study started on 2020-01-16. Estimated completion is 2022-07-15.

What interventions are being tested in trial NCT04171700?

The interventions under investigation include: Rucaparib (DRUG).

Who is sponsoring clinical trial NCT04171700?

This trial is sponsored by pharmaand, which has 15 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04171700's enrollment target sits among peer trials

83 828th of 2000 higher than 1,171 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04171700, the US trial registry maintained by the National Library of Medicine. NCT04171700 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.