Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04154111 · ClinicalTrials.gov registry record · NA
Theta Burst Stimulation as a Tool to Decrease Drinking in Treatment-seeking Alcohol Users
A NA study, sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- NA
- Development phase
- 147
- Enrollment target
NCT04154111: Completed NA study, sponsored by Wake Forest University Health Sciences.
NCT04154111 is a NA study that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 147 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04154111, a NA study, has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- NA
- Development phase
- 147 participants
- Enrollment target
Study Summary
There is growing interest in the utilization of transcranial magnetic stimulation (TMS) as a novel, non-pharmacologic approach to decreasing alcohol use among treatment-seeking individuals with Alcohol Use Disorder (AUD). The results of this study will be used to determine which of the 2 proposed TMS strategies has a larger effect on drinking behavior (% days abstinent, % heavy drinking days) as well as alcohol cue-reactivity in a 4 month period. These data will pave the way for TMS to be used as an innovative, new treatment option for individuals with AUD.
Primary Outcome
These outcomes will be measured with urine ETG and CDT drug screens collected monthly up to 4 months.
Interventions
- DEVICE Real TBS to the vmPFC
- DEVICE Sham TBS to the vmPFC
- DEVICE Real TBS to the dlPFC
- DEVICE Sham TBS to the dlPFC
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 147 participants |
| Start Date | 2020-05-26 |
| Est. Completion | 2026-02-09 |
| Phase | NA |
What the finished NCT04154111 record still lists
NCT04154111 is an interventional study that assigns participants to a tested intervention. The registered 147 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 4 interventions - of which Real TBS to the vmPFC is the first listed.
NCT04154111 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04154111 about?
NCT04154111 is a clinical study titled "Theta Burst Stimulation as a Tool to Decrease Drinking in Treatment-seeking Alcohol Users". There is growing interest in the utilization of transcranial magnetic stimulation (TMS) as a novel, non-pharmacologic approach to decreasing alcohol use among treatment-seeking individuals with Alcohol Use Disorder (AUD). The results of this study will be used to determine which of the 2 proposed TM...
What is the current status of trial NCT04154111?
This trial is currently completed. It is a NA study. The enrollment target is 147 participants. The study started on 2020-05-26. Estimated completion is 2026-02-09.
What interventions are being tested in trial NCT04154111?
The interventions under investigation include: Real TBS to the vmPFC (DEVICE), Sham TBS to the vmPFC (DEVICE), Real TBS to the dlPFC (DEVICE), Sham TBS to the dlPFC (DEVICE).
Who is sponsoring clinical trial NCT04154111?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04154111's enrollment target sits among peer trials
147 703rd of 2000 higher than 1,297 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04396613 · 147 participants · NA
Wound Closure Techniques in Primary Spine Surgery
- NCT04851119 · 147 participants · Phase 1
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
- NCT05523947 · 147 participants · Phase 1
Clinical Trial of YH32367 in Patients With HER2 Positive Locally Advanced or Metastatic Solid Tumor
- NCT06121843 · 147 participants · Phase 1
A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI