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NCT04153578 · ClinicalTrials.gov registry record
Time to Lose the Weight? Comparison of Weight-based and Non-weight-based Vasopressors for Septic Shock
A clinical trial of Septic Shock and Weight, Body, sponsored by Methodist Health System.
- Completed
- Registry status
- 945
- Enrollment target
- 1
- Study location
NCT04153578 is a study of Septic Shock and Weight, Body that has completed, run by Methodist Health System. The registered enrollment target is 945 participants, below the 5,020-participant average among 24 other Septic Shock trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04153578, a study of Septic Shock and Weight, Body, has completed, sponsored by Methodist Health System.
- COMPLETED
- Registry status
- 945 participants
- Enrollment target
- 1
- Study location
Study Summary
At present, there is conflicting evidence regarding outcomes in patients with septic shock receiving weight-based vasopressor (WBVP) versus non-weight-based vasopressor (NWBVP) dosing strategies. At MCMC, a weight-based strategy is in place whereas MDMC, MMMC and MRMC currently utilize a non-weight-based dosing strategy. Obese patients (BMI \> 30) receiving either strategy may potentially be receiving substantially more or less vasopressor exposure compared to their non-obese (BMI \< 30) counterparts. Determining total vasopressor exposure and assessing clinical outcomes would benefit our institution and others by providing optimal vasopressor dosing strategies in obese and non-obese patients. There is a difference in clinical outcomes between patients receiving weight-based and non-weight-based vasopressor dosing strategies. There is a difference in total vasopressor exposure between obese and non-obese patients utilizing WBVP and NWBVP strategies.
Conditions Studied
Study Locations (1)
Texas
- Methodist Dallas Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 945 participants |
| Start Date | 2019-11-04 |
| Est. Completion | 2020-06-22 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04153578
The ClinicalTrials.gov registry entry for NCT04153578 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 945 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,020-participant average among 24 other Septic Shock trials with a reported enrollment target (81% lower). The listed sponsor is Methodist Health System, which has 125 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Septic Shock appearing as the primary indexed condition, and to 0 interventions.
NCT04153578 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT04153578 about?
NCT04153578 is a clinical study titled "Time to Lose the Weight? Comparison of Weight-based and Non-weight-based Vasopressors for Septic Shock". At present, there is conflicting evidence regarding outcomes in patients with septic shock receiving weight-based vasopressor (WBVP) versus non-weight-based vasopressor (NWBVP) dosing strategies. At MCMC, a weight-based strategy is in place whereas MDMC, MMMC and MRMC currently utilize a non-weight-...
What is the current status of trial NCT04153578?
This trial is currently completed. The enrollment target is 945 participants. The study started on 2019-11-04. Estimated completion is 2020-06-22.
What conditions does trial NCT04153578 study?
This clinical trial studies the following conditions: Septic Shock, Weight, Body.
Who is sponsoring clinical trial NCT04153578?
This trial is sponsored by Methodist Health System, which has 125 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04153578 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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