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NCT04143516 · ClinicalTrials.gov registry record · Phase 2

Tissue Analysis After Tumor Ablation for Liver Metastases Leading to Immediate Retreatment

A Phase 2 study of Liver Metastases, sponsored by Memorial Sloan Kettering Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
200
Enrollment target
1
Study location

NCT04143516: Recruiting Phase 2 study of Liver Metastases, sponsored by Memorial Sloan Kettering Cancer Center.

NCT04143516 is a Phase 2 study of Liver Metastases that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 200 participants, above the 61-participant average among 27 other Liver Metastases trials with a reported enrollment target (228% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04143516, a Phase 2 study of Liver Metastases, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
200 participants
Enrollment target
1
Study location

Study Summary

This study will see whether collecting and analyzing needle biopsy samples from cancer liver metastases after a tumor ablation procedure will be able to identify cancer cells that are still alive. The results of these biopsies could help determine the next treatment for your cancer, but the biopsies could cause side effects.

Primary Outcome

will be measured according to RECIST and PERCIST 1.0. The first CT and PET scan taken after ablation will be considered the new baseline for subsequent comparisons and measurements.

Conditions Studied

Interventions

  • DIAGNOSTIC_TEST PET/CT Scan
  • DIAGNOSTIC_TEST [18-F]- FDG - PET
  • PROCEDURE Tumor ablation (TA)

Study Locations (1)

New York

  • Memorial Sloan Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2019-10-25
Est. Completion 2026-10
Phase Phase 2
Memorial Sloan Kettering Cancer Center

1,884 total trials

What NCT04143516 shows while recruiting

NCT04143516 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, above the 61-participant average among 27 other Liver Metastases trials with a reported enrollment target (228% higher).

The record links to 1 condition, with Liver Metastases appearing as the primary indexed condition, and to 3 interventions - of which PET/CT Scan is the first listed.

NCT04143516 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT04143516 about?

NCT04143516 is a clinical study titled "Tissue Analysis After Tumor Ablation for Liver Metastases Leading to Immediate Retreatment". This study will see whether collecting and analyzing needle biopsy samples from cancer liver metastases after a tumor ablation procedure will be able to identify cancer cells that are still alive. The results of these biopsies could help determine the next treatment for your cancer, but the biopsies...

What is the current status of trial NCT04143516?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2019-10-25. Estimated completion is 2026-10.

What conditions does trial NCT04143516 study?

This clinical trial studies the following conditions: Liver Metastases.

What interventions are being tested in trial NCT04143516?

The interventions under investigation include: PET/CT Scan (DIAGNOSTIC_TEST), [18-F]- FDG - PET (DIAGNOSTIC_TEST), Tumor ablation (TA) (PROCEDURE).

Who is sponsoring clinical trial NCT04143516?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04143516 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Liver Metastases

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04143516's enrollment target sits among peer trials

200 3rd of 27 higher than 25 of 27 other Liver Metastases trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Liver Metastases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04143516, the US trial registry maintained by the National Library of Medicine. NCT04143516 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.