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NCT04141046 · ClinicalTrials.gov registry record · NA
LUPUS Brain: tACS to Target the Neurophysiology of Depression, Cognitive Deficits, and Pain in Patients With SLE
A NA study, sponsored by University of North Carolina, Chapel Hill.
- Terminated
- Registry status
- NA
- Development phase
- 4
- Enrollment target
NCT04141046: Clinical Trial NA study, sponsored by University of North Carolina, Chapel Hill.
NCT04141046 is a NA study that was terminated before completion, run by University of North Carolina, Chapel Hill. The registered enrollment target is 4 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04141046, a NA study, was terminated before completion, sponsored by University of North Carolina, Chapel Hill.
- TERMINATED
- Registry status
- NA
- Development phase
- 4 participants
- Enrollment target
Study Summary
The purpose of this study is to investigate the effects of a type of non-invasive transcranial alternating current stimulation (tACS) on patients diagnosed with systemic lupus erythematosus (SLE) who are experiencing depression. Targeting depression in patients with SLE may provide benefit to these patients, as there is a clear relationship between chronic pain and depression. The investigators propose that a tACS stimulation montage that was previously used in depression could be beneficial to patients with SLE, resulting in reduced depression symptoms, thus resulting in reduced chronic pain and cognitive difficulties.
Primary Outcome
Change in alpha oscillation power (8-12 Hz) will be measured between resting state electroencephalogram (RSEEG) recordings.
Interventions
- DEVICE XCSITE100 Stimulator - Individualized theta-tACS
- DEVICE XCSITE100 Stimulator - Individualized alpha-tACS
- DEVICE XCSITE100 Stimulator - Active Sham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2019-01-01 |
| Est. Completion | 2023-09-15 |
| Phase | NA |
Why NCT04141046 stopped before completion
NCT04141046 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 3 interventions - of which XCSITE100 Stimulator - Individualized theta-tACS is the first listed.
NCT04141046 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04141046 about?
NCT04141046 is a clinical study titled "LUPUS Brain: tACS to Target the Neurophysiology of Depression, Cognitive Deficits, and Pain in Patients With SLE". The purpose of this study is to investigate the effects of a type of non-invasive transcranial alternating current stimulation (tACS) on patients diagnosed with systemic lupus erythematosus (SLE) who are experiencing depression. Targeting depression in patients with SLE may provide benefit to these...
What is the current status of trial NCT04141046?
This trial is currently terminated. It is a NA study. The enrollment target is 4 participants. The study started on 2019-01-01. Estimated completion is 2023-09-15.
What interventions are being tested in trial NCT04141046?
The interventions under investigation include: XCSITE100 Stimulator - Individualized theta-tACS (DEVICE), XCSITE100 Stimulator - Individualized alpha-tACS (DEVICE), XCSITE100 Stimulator - Active Sham (DEVICE).
Who is sponsoring clinical trial NCT04141046?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04141046's enrollment target sits among peer trials
4 1996th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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