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NCT04133363 · ClinicalTrials.gov registry record · NA
To Compare Ridge Preservation Technique Using Leukocyte Platelet Rich Fibrin (L-PRF) and Freeze-dried Bone Allograft (FDBA) Layered Technique vs L-PRF/FDBA and L-PRF Alone in Influencing Quantity and Quality of New Bone Formation in Grafted Extraction Sockets
A NA study of Ridge Preservation, sponsored by University of Alabama at Birmingham.
- Completed
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT04133363: Completed NA study of Ridge Preservation, sponsored by University of Alabama at Birmingham.
NCT04133363 is a NA study of Ridge Preservation that has completed, run by University of Alabama at Birmingham. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04133363, a NA study of Ridge Preservation, has completed, sponsored by University of Alabama at Birmingham.
- COMPLETED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will evaluate the effect of Leukocyte Platelet Rich Fibrin and freeze-dried bone allograft in a layered technique on the bone quantity and quality following socket grafting in preparation for endosseous implant placement. Pre (baseline)- and post-grafting (3 months) clinical as well as 2- and 3-dimensional radiographic measurements will be used to evaluate the dimensional ridge changes between sites grafted with L-PRF/FDBA layered technique vs. L-PRF/FDBA and L-PRF alone. Histological analysis will be performed by a bone biopsy taken at time of surgical re-entry (after 3 months) of grafted sites to place the dental implant and assessed for differences in new bone formation between the three types of graft.
Primary Outcome
Compare quantitative clinical alveolar ridge dimensions (in mm) 3 months after ridge preservation between the three groups. Clinically we will measure the bone width of the ridge at time of extraction and after three months during the implant placement procedure. The dimensional changes will be calculated by subtracting the follow measurement from the initial measurement.
Conditions Studied
Interventions
- PROCEDURE Ridge preservation using L-PRF/FDBA layered technique
- PROCEDURE Ridge preservation using L-PRF/FDBA
- PROCEDURE Ridge preservation using L-PRF
Study Locations (1)
Alabama
- University of Alabama at Birmingham - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2020-06-15 |
| Est. Completion | 2023-01-31 |
| Phase | NA |
What the finished NCT04133363 record still lists
NCT04133363 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Ridge Preservation appearing as the primary indexed condition, and to 3 interventions - of which Ridge preservation using L-PRF/FDBA layered technique is the first listed.
NCT04133363 reports a single indexed study location in Alabama.
Frequently Asked Questions
What is clinical trial NCT04133363 about?
NCT04133363 is a clinical study titled "To Compare Ridge Preservation Technique Using Leukocyte Platelet Rich Fibrin (L-PRF) and Freeze-dried Bone Allograft (FDBA) Layered Technique vs L-PRF/FDBA and L-PRF Alone in Influencing Quantity and Quality of New Bone Formation in Grafted Extraction Sockets". This study will evaluate the effect of Leukocyte Platelet Rich Fibrin and freeze-dried bone allograft in a layered technique on the bone quantity and quality following socket grafting in preparation for endosseous implant placement. Pre (baseline)- and post-grafting (3 months) clinical as well as 2...
What is the current status of trial NCT04133363?
This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2020-06-15. Estimated completion is 2023-01-31.
What conditions does trial NCT04133363 study?
This clinical trial studies the following conditions: Ridge Preservation.
What interventions are being tested in trial NCT04133363?
The interventions under investigation include: Ridge preservation using L-PRF/FDBA layered technique (PROCEDURE), Ridge preservation using L-PRF/FDBA (PROCEDURE), Ridge preservation using L-PRF (PROCEDURE).
Who is sponsoring clinical trial NCT04133363?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04133363 being conducted?
This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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30 1593rd of 2000 higher than 299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
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Source ClinicalTrials.gov registry export · 2026-08-08
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