Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING Phase 2

Study of RV001V in Biochemical Failure Following Curatively Intended Therapy For Localized Prostate Cancer

NCT04114825 · View on ClinicalTrials.gov ↗

Study Summary

This Phase II trial will enroll approximately 180 adult male patients with an earlier histologic diagnosis of prostatic adenocarcinoma and a biochemical recurrence (BCR) within 3 years of radical prostatectomy (RP) or definitive RT and no distant metastasis or locoregional recurrence. The trial is a randomized placebo-controlled double-blind study of a peptide cancer vaccine (RV001V).

Conditions Studied

Interventions

  • OTHER Placebo
  • BIOLOGICAL RV001V

Study Locations (20)

Other

  • Gent University Hospital — Ghent
  • CHU de Liège — Liège
  • Hôpital Erasme — Liège
  • Aalborg University, Departmen of Urology — Aalborg
  • Aarhus University Hospital, Department of Urology — Aarhus
  • Rigshospitalet, Copenhagen Prostate Cancer Center — Copenhagen
  • Herlev & Gentofte Hospital, Department of Urology — Herlev
  • Urinvejskirurgisk afdeling, Hospitalsenheden Vest — Holstebro
  • Odense University Hospital, Deparment of Urology — Odense
  • Meilahti Tower Hospital — Helsinki
  • Oulu University Hospital — Oulu
  • Seinajoki Central Hospital — Seinäjoki
  • Tampere University Hospital — Tampere

Florida

  • Tampa Bay Medical Research — Clearwater

Maryland

  • Chesapeake Urology Research Associates — Towson

Nebraska

  • GU Research Network/Urology Cancer Center — Omaha

Nevada

  • Comprehensive Cancer Centers of Nevada — Las Vegas

New York

  • Icahn School of Medicine at Mount Sinai Hospitals — New York

South Carolina

  • Carolina Urologic Research Center — Myrtle Beach

Texas

  • The Urology Place — San Antonio

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2019-11-19
Est. Completion 2022-11
Phase Phase 2

Sponsor

RhoVac APS

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04114825

The ClinicalTrials.gov registry entry for NCT04114825 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 180 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is RhoVac APS, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Prostate Cancer Recurrent appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04114825 reports 20 study locations spanning 8 distinct geographic areas — top geographies include Other, Florida, Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04114825 about?

NCT04114825 is a clinical study titled "Study of RV001V in Biochemical Failure Following Curatively Intended Therapy For Localized Prostate Cancer". This Phase II trial will enroll approximately 180 adult male patients with an earlier histologic diagnosis of prostatic adenocarcinoma and a biochemical recurrence (BCR) within 3 years of radical prostatectomy (RP) or definitive RT and no distant metastasis or locoregional recurrence. The trial is a...

What is the current status of trial NCT04114825?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 180 participants. The study started on 2019-11-19. Estimated completion is 2022-11.

What conditions does trial NCT04114825 study?

This clinical trial studies the following conditions: Prostate Cancer Recurrent. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04114825?

The interventions under investigation include: Placebo (OTHER), RV001V (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04114825?

This trial is sponsored by RhoVac APS, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04114825 being conducted?

This trial has 20 study locations across Florida, Maryland, Nebraska, Nevada, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial