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NCT04110535 · ClinicalTrials.gov registry record · Phase 1
Abuse Potential of Intravenous Remimazolam Compared to Midazolam and Placebo in Recreational CNS Depressant Users
A Phase 1 study, sponsored by Paion UK.
- Completed
- Registry status
- Phase 1
- Development phase
- 83
- Enrollment target
NCT04110535: Completed Phase 1 study, sponsored by Paion UK.
NCT04110535 is a Phase 1 study that has completed, run by Paion UK. The registered enrollment target is 83 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (38% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04110535, a Phase 1 study, has completed, sponsored by Paion UK.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 83 participants
- Enrollment target
Study Summary
A double-blind, randomized crossover study to assess the subjective abuse potential of intravenous remimazolam compared to midazolam and placebo in recreational CNS depressant users
Primary Outcome
Maximum effect (Emax) on the bipolar Drug Liking visual analogue scale (VAS)
Interventions
- OTHER Saline
- DRUG Midazolam
- DRUG Remimazolam
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 83 participants |
| Start Date | 2015-06-23 |
| Est. Completion | 2015-10-06 |
| Phase | Phase 1 |
What the finished NCT04110535 record still lists
NCT04110535 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 83 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (38% higher).
The record links to 0 conditions, and to 3 interventions - of which Saline is the first listed.
NCT04110535 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04110535 about?
NCT04110535 is a clinical study titled "Abuse Potential of Intravenous Remimazolam Compared to Midazolam and Placebo in Recreational CNS Depressant Users". A double-blind, randomized crossover study to assess the subjective abuse potential of intravenous remimazolam compared to midazolam and placebo in recreational CNS depressant users
What is the current status of trial NCT04110535?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 83 participants. The study started on 2015-06-23. Estimated completion is 2015-10-06.
What interventions are being tested in trial NCT04110535?
The interventions under investigation include: Saline (OTHER), Midazolam (DRUG), Remimazolam (DRUG).
Who is sponsoring clinical trial NCT04110535?
This trial is sponsored by Paion UK, which has 9 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04110535's enrollment target sits among peer trials
83 665th of 2000 higher than 1,332 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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