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NCT04101968 · ClinicalTrials.gov registry record
The GBA Multimodal Study in Parkinson's Disease
A clinical trial of Parkinson Disease and Gaucher Disease, sponsored by Pacific Parkinson's Research Centre.
- Recruiting
- Registry status
- 25
- Enrollment target
- 3
- Study locations
NCT04101968: Recruiting study of Parkinson Disease and Gaucher Disease, sponsored by Pacific Parkinson's Research Centre.
NCT04101968 is a study of Parkinson Disease and Gaucher Disease that is actively recruiting participants, run by Pacific Parkinson's Research Centre. The registered enrollment target is 25 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (100% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04101968, a study of Parkinson Disease and Gaucher Disease, is actively recruiting participants, sponsored by Pacific Parkinson's Research Centre.
- RECRUITING
- Registry status
- 25 participants
- Enrollment target
- 3
- Study locations
Study Summary
This study plans to analyze the molecular and clinical mechanisms of the relationship between the GBA mutations and Parkinson's disease. This will be assessed through the use of advanced neuroimaging techniques called PET (positron emission tomography) to study the accumulation of the tau protein and the dysfunction of acetylcholine and dopamine in the brain of people with a mutation in the GBA gene, with and without Parkinson's disease. The ingestigators will also use a technology-based assessment to study the typing patterns as possible biomarkers of early motor dysfunctions.
Primary Outcome
11C-PMP PET
Conditions Studied
Interventions
- DIAGNOSTIC_TEST PET scan
- DIAGNOSTIC_TEST neuroQWERTY
Study Locations (3)
Oregon
- Oregon Health & Science University - Portland
Washington
- University of Washington - Seattle
British Columbia
- Pacific Parkinson's Research Centre | University of British Columbia - Vancouver
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2019-05-01 |
| Est. Completion | 2025-12-30 |
What NCT04101968 shows while recruiting
NCT04101968 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (100% lower).
The record links to 3 conditions, with Parkinson Disease appearing as the primary indexed condition, and to 2 interventions - of which PET scan is the first listed.
NCT04101968 reports a single indexed study location in Oregon, Washington, British Columbia.
Frequently Asked Questions
What is clinical trial NCT04101968 about?
NCT04101968 is a clinical study titled "The GBA Multimodal Study in Parkinson's Disease". This study plans to analyze the molecular and clinical mechanisms of the relationship between the GBA mutations and Parkinson's disease. This will be assessed through the use of advanced neuroimaging techniques called PET (positron emission tomography) to study the accumulation of the tau protein an...
What is the current status of trial NCT04101968?
This trial is currently recruiting. The enrollment target is 25 participants. The study started on 2019-05-01. Estimated completion is 2025-12-30.
What conditions does trial NCT04101968 study?
This clinical trial studies the following conditions: Parkinson Disease, Gaucher Disease, GBA Gene Mutation.
What interventions are being tested in trial NCT04101968?
The interventions under investigation include: PET scan (DIAGNOSTIC_TEST), neuroQWERTY (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04101968?
This trial is sponsored by Pacific Parkinson's Research Centre, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04101968 being conducted?
This trial has 3 study locations across Oregon, Washington, British Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04101968's enrollment target sits among peer trials
25 225th of 297 higher than 67 of 297 other Parkinson Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinson Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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