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NCT04085406 · ClinicalTrials.gov registry record · NA
DBS of the SCC for the Treatment of Medically Refractory CLBP
A NA study of Chronic Low Back Pain, sponsored by University of California, Los Angeles.
- Recruiting
- Registry status
- NA
- Development phase
- 16
- Enrollment target
- 2
- Study locations
NCT04085406: Recruiting NA study of Chronic Low Back Pain, sponsored by University of California, Los Angeles.
NCT04085406 is a NA study of Chronic Low Back Pain that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 16 participants, below the 592-participant average among 71 other Chronic Low Back Pain trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04085406, a NA study of Chronic Low Back Pain, is actively recruiting participants, sponsored by University of California, Los Angeles.
- RECRUITING
- Registry status
- NA
- Development phase
- 16 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this study is to evaluate the feasibility and preliminary efficacy of deep brain stimulation of the subgenual cingulate cortex for the treatment of chronic medically-refractory low back pain using a randomized double-blind crossover design.
Primary Outcome
The visual analog scale for pain is a continuous horizontal scale of length 100 mm with the extremes of pain expressed on either end (0 = no pain, 10 = worst pain). The change on the VAS from active stimulation compared to baseline and sham stimulation will be calculated.
Conditions Studied
Interventions
- DEVICE Deep Brain Stimulation of the Subgenus Cingulate Cortex
Study Locations (2)
California
- University of California Los Angeles - Los Angeles
Texas
- University of Texas Southwestern Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2021-05-01 |
| Est. Completion | 2027-06-30 |
| Phase | NA |
What NCT04085406 shows while recruiting
NCT04085406 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 592-participant average among 71 other Chronic Low Back Pain trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Chronic Low Back Pain appearing as the primary indexed condition, and to 1 intervention - of which Deep Brain Stimulation of the Subgenus Cingulate Cortex is the first listed.
NCT04085406 reports a single indexed study location in California, Texas.
Frequently Asked Questions
What is clinical trial NCT04085406 about?
NCT04085406 is a clinical study titled "DBS of the SCC for the Treatment of Medically Refractory CLBP". The purpose of this study is to evaluate the feasibility and preliminary efficacy of deep brain stimulation of the subgenual cingulate cortex for the treatment of chronic medically-refractory low back pain using a randomized double-blind crossover design.
What is the current status of trial NCT04085406?
This trial is currently recruiting. It is a NA study. The enrollment target is 16 participants. The study started on 2021-05-01. Estimated completion is 2027-06-30.
What conditions does trial NCT04085406 study?
This clinical trial studies the following conditions: Chronic Low Back Pain.
What interventions are being tested in trial NCT04085406?
The interventions under investigation include: Deep Brain Stimulation of the Subgenus Cingulate Cortex (DEVICE).
Who is sponsoring clinical trial NCT04085406?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04085406 being conducted?
This trial has 2 study locations across California, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Low Back Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04085406's enrollment target sits among peer trials
16 70th of 71 higher than 2 of 71 other Chronic Low Back Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Low Back Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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