Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04048616 · ClinicalTrials.gov registry record · NA
Impact of Protein and Alkali Supplementation on Skeletal Muscle in Older Adults
A NA study of Muscle Loss and Age-Related Sarcopenia, sponsored by Tufts University.
- Completed
- Registry status
- NA
- Development phase
- 141
- Enrollment target
- 1
- Study location
NCT04048616: Completed NA study of Muscle Loss and Age-Related Sarcopenia, sponsored by Tufts University.
NCT04048616 is a NA study of Muscle Loss and Age-Related Sarcopenia that has completed, run by Tufts University. The registered enrollment target is 141 participants, above the 74-participant average among 6 other Muscle Loss trials with a reported enrollment target (91% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04048616, a NA study of Muscle Loss and Age-Related Sarcopenia, has completed, sponsored by Tufts University.
- COMPLETED
- Registry status
- NA
- Development phase
- 141 participants
- Enrollment target
- 1
- Study location
Study Summary
The central hypothesis is that higher protein intake and a neutralizing alkaline salt supplement will improve muscle performance and mass, compared to their respective placebos, in older men and postmenopausal women.
Primary Outcome
Double leg press peak power at 70% of the 1 repetition maximum
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT whey protein isolate
- DIETARY_SUPPLEMENT potassium bicarbonate (KHCO3)
- OTHER microcrystalline cellulose
- OTHER maltodextrin powder
Study Locations (1)
Massachusetts
- Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 141 participants |
| Start Date | 2021-07-01 |
| Est. Completion | 2023-12-21 |
| Phase | NA |
What the finished NCT04048616 record still lists
NCT04048616 is an interventional study that assigns participants to a tested intervention. The registered 141 participants enrollment target is mid-sized for trials with a published cap, above the 74-participant average among 6 other Muscle Loss trials with a reported enrollment target (91% higher).
The record links to 2 conditions, with Muscle Loss appearing as the primary indexed condition, and to 4 interventions - of which whey protein isolate is the first listed.
NCT04048616 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04048616 about?
NCT04048616 is a clinical study titled "Impact of Protein and Alkali Supplementation on Skeletal Muscle in Older Adults". The central hypothesis is that higher protein intake and a neutralizing alkaline salt supplement will improve muscle performance and mass, compared to their respective placebos, in older men and postmenopausal women.
What is the current status of trial NCT04048616?
This trial is currently completed. It is a NA study. The enrollment target is 141 participants. The study started on 2021-07-01. Estimated completion is 2023-12-21.
What conditions does trial NCT04048616 study?
This clinical trial studies the following conditions: Muscle Loss, Age-Related Sarcopenia.
What interventions are being tested in trial NCT04048616?
The interventions under investigation include: whey protein isolate (DIETARY_SUPPLEMENT), potassium bicarbonate (KHCO3) (DIETARY_SUPPLEMENT), microcrystalline cellulose (OTHER), maltodextrin powder (OTHER).
Who is sponsoring clinical trial NCT04048616?
This trial is sponsored by Tufts University, which has 163 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04048616 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Muscle Loss
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
YOOMI: Effect of Gamified Physical Therapy Exercise Software on Inpatient Mobility
RECRUITING · NA
-
PRotein Optimization With eXercise to Improve MUscle Mass and Functional outcomeS
RECRUITING · NA
-
Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease
RECRUITING · NA
-
Examining the Effects of Vivo on Physical Function and Glycemic Level in Sedentary Older With Prediabetes.
ACTIVE NOT RECRUITING · NA
-
Effects of Dietary Protein on Musculoskeletal Health During Calorie Deficiency
COMPLETED · NA
-
CFTR Modulator Effects on Bone and Muscle in Adults With Cystic Fibrosis
ACTIVE NOT RECRUITING
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03042962 · 141 participants
Brain Networks in Dystonia
- NCT04378439 · 141 participants · NA
Appalachian Partnership to Reduce Disparities (Aim 2)
- NCT04775485 · 141 participants · Phase 2
A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors
- NCT05040360 · 141 participants · Phase 2
Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI