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NCT04043806 · ClinicalTrials.gov registry record · Phase 3

A Study Evaluating the Long-term Safety of VX-445 Combination Therapy

A Phase 3 study, sponsored by Vertex Pharmaceuticals Incorporated.

Completed
Registry status
Phase 3
Development phase
458
Enrollment target

NCT04043806 is a Phase 3 study that has completed, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 458 participants.

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The verdict

NCT04043806, a Phase 3 study, has completed, sponsored by Vertex Pharmaceuticals Incorporated.

COMPLETED
Registry status
Phase 3
Development phase
458 participants
Enrollment target

Study Summary

This study evaluated the long-term safety and tolerability of elexacaftor (ELX), tezacaftor (TEZ), and ivacaftor (IVA) triple combination (TC) treatment in participants with cystic fibrosis (CF).

Interventions

  • DRUG IVA
  • DRUG ELX/TEZ/IVA

Trial Details

FieldValue
Enrollment Target 458 participants
Start Date 2019-08-09
Est. Completion 2022-12-14
Phase Phase 3

Sponsor

Vertex Pharmaceuticals Incorporated

191 total trials

What the Registry Record Tells You About NCT04043806

The ClinicalTrials.gov registry entry for NCT04043806 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 458 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vertex Pharmaceuticals Incorporated, which has 191 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which IVA is the first listed.

NCT04043806 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04043806 about?

NCT04043806 is a clinical study titled "A Study Evaluating the Long-term Safety of VX-445 Combination Therapy". This study evaluated the long-term safety and tolerability of elexacaftor (ELX), tezacaftor (TEZ), and ivacaftor (IVA) triple combination (TC) treatment in participants with cystic fibrosis (CF).

What is the current status of trial NCT04043806?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 458 participants. The study started on 2019-08-09. Estimated completion is 2022-12-14.

What interventions are being tested in trial NCT04043806?

The interventions under investigation include: IVA (DRUG), ELX/TEZ/IVA (DRUG).

Who is sponsoring clinical trial NCT04043806?

This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.