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NCT04032717 · ClinicalTrials.gov registry record · Phase 1

Griffithsin-based Rectal Microbicide for PREvention of Viral ENTry (PREVENT)

A Phase 1 study, sponsored by Rhonda Brand.

Terminated
Registry status
Phase 1
Development phase
18
Enrollment target

NCT04032717 is a Phase 1 study that was terminated before completion, run by Rhonda Brand. The registered enrollment target is 18 participants.

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The verdict

NCT04032717, a Phase 1 study, was terminated before completion, sponsored by Rhonda Brand.

TERMINATED
Registry status
Phase 1
Development phase
18 participants
Enrollment target

Study Summary

This is the first-in-human clinical study to see if a single dose of an investigational enema made from a modified plant protein called Q-Griffithsin is safe, tolerated, and acceptable for use by healthy adults 18-45 years of age who practice receptive anal intercourse.

Interventions

  • DRUG Q-Griffithsin (Q-GRFT) enema
  • OTHER Placebo enema

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2019-07-10
Est. Completion 2021-02-04
Phase Phase 1

Sponsor

Rhonda Brand

2 total trials

What the Registry Record Tells You About NCT04032717

The ClinicalTrials.gov registry entry for NCT04032717 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Rhonda Brand, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Q-Griffithsin (Q-GRFT) enema is the first listed.

NCT04032717 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04032717 about?

NCT04032717 is a clinical study titled "Griffithsin-based Rectal Microbicide for PREvention of Viral ENTry (PREVENT)". This is the first-in-human clinical study to see if a single dose of an investigational enema made from a modified plant protein called Q-Griffithsin is safe, tolerated, and acceptable for use by healthy adults 18-45 years of age who practice receptive anal intercourse.

What is the current status of trial NCT04032717?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2019-07-10. Estimated completion is 2021-02-04.

What interventions are being tested in trial NCT04032717?

The interventions under investigation include: Q-Griffithsin (Q-GRFT) enema (DRUG), Placebo enema (OTHER).

Who is sponsoring clinical trial NCT04032717?

This trial is sponsored by Rhonda Brand, which has 2 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.