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NCT04010461 · ClinicalTrials.gov registry record · NA
Theta Burst Transcranial Magnetic Stimulation of Fronto-parietal Networks: Modulation by Mental State
A NA study of Healthy, sponsored by University of Michigan.
- Completed
- Registry status
- NA
- Development phase
- 53
- Enrollment target
- 1
- Study location
NCT04010461 is a NA study of Healthy that has completed, run by University of Michigan. The registered enrollment target is 53 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04010461, a NA study of Healthy, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- NA
- Development phase
- 53 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to improve understanding of the way transcranial magnetic stimulation (TMS), a form of non-invasive brain stimulation, affects the brain. The study hypothesis that when theta burst stimulation (TBS) is applied during a controlled mental state, network changes will be facilitated, compared to stimulation when mental state is uncontrolled. This study will focus on the dorsolateral prefrontal cortex (dlPFC) and the associated frontoparietal network (FPN), which subserves cognitive control - the ability to flexibly adapt and regulate behavior, an ability known to be impaired in neuropsychiatric conditions such as depression and dementia. Healthy volunteers that qualify for this study will have psychological assessments and cognitive measures (due to Covid, some of these were done via teleconference), as well as functional Magnetic Resonance Imaging (fMRI) scans, completed after administration of TMS. Participants will be asked to come in for a total of five visits that include; a screening and assessment visit; a baseline functional magnetic resonance imaging (fMRI) scan, followed by TMS session; Visits 3, 4, and 5 will be the experimental TMS session, followed by fMRI scan.
Conditions Studied
Interventions
- DEVICE TMS
- BEHAVIORAL n-back working memory task
Study Locations (1)
Michigan
- University of Michigan - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 53 participants |
| Start Date | 2019-11-11 |
| Est. Completion | 2022-03-29 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04010461
The ClinicalTrials.gov registry entry for NCT04010461 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 53 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (92% lower). The listed sponsor is University of Michigan, which has 1,327 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which TMS is the first listed.
NCT04010461 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.
Frequently Asked Questions
What is clinical trial NCT04010461 about?
NCT04010461 is a clinical study titled "Theta Burst Transcranial Magnetic Stimulation of Fronto-parietal Networks: Modulation by Mental State". The purpose of this study is to improve understanding of the way transcranial magnetic stimulation (TMS), a form of non-invasive brain stimulation, affects the brain. The study hypothesis that when theta burst stimulation (TBS) is applied during a controlled mental state, network changes will be fac...
What is the current status of trial NCT04010461?
This trial is currently completed. It is a NA study. The enrollment target is 53 participants. The study started on 2019-11-11. Estimated completion is 2022-03-29.
What conditions does trial NCT04010461 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT04010461?
The interventions under investigation include: TMS (DEVICE), n-back working memory task (BEHAVIORAL).
Who is sponsoring clinical trial NCT04010461?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04010461 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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