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NCT04007081 · ClinicalTrials.gov registry record · NA
Salivary Gland Autotransplantation for Treatment of XRT Induced Xerostomia
A NA study, sponsored by University of Wisconsin, Madison.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
NCT04007081 is a NA study that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 12 participants.
The verdict
NCT04007081, a NA study, has completed, sponsored by University of Wisconsin, Madison.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
Study Summary
Xerostomia, or dry mouth, is a common side effect of head neck radiation. Current treatment options for radiation-induced xerostomia are generally supportive in nature. Most of these supportive interventions do not reverse xerostomia and are palliative in intent. The investigators propose that autotransplantation of marrow-derived mesenchymal stromal cells (MSCs) in salivary glands post-RT or post-chemoradiation therapy (CRT) may provide an innovative remedy to treat xerostomia and restore quality of life. Participants can expect to be on study for up to 6 months.
Interventions
- PROCEDURE Bone Marrow Aspiration
- DIAGNOSTIC_TEST Ultrasound Imaging of Salivary Glands
- OTHER Salivary Assay
- OTHER Quality of Life Instruments
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2019-10-18 |
| Est. Completion | 2021-03-10 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04007081
The ClinicalTrials.gov registry entry for NCT04007081 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Wisconsin, Madison, which has 1,039 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Bone Marrow Aspiration is the first listed.
NCT04007081 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04007081 about?
NCT04007081 is a clinical study titled "Salivary Gland Autotransplantation for Treatment of XRT Induced Xerostomia". Xerostomia, or dry mouth, is a common side effect of head neck radiation. Current treatment options for radiation-induced xerostomia are generally supportive in nature. Most of these supportive interventions do not reverse xerostomia and are palliative in intent. The investigators propose that auto...
What is the current status of trial NCT04007081?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2019-10-18. Estimated completion is 2021-03-10.
What interventions are being tested in trial NCT04007081?
The interventions under investigation include: Bone Marrow Aspiration (PROCEDURE), Ultrasound Imaging of Salivary Glands (DIAGNOSTIC_TEST), Salivary Assay (OTHER), Quality of Life Instruments (OTHER).
Who is sponsoring clinical trial NCT04007081?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
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