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NCT04005976 · ClinicalTrials.gov registry record
Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease
A clinical trial of Aortic Aneurysm and Aortic Dissection, sponsored by The University of Texas Health Science Center, Houston.
- Recruiting
- Registry status
- 5,000
- Enrollment target
- 20
- Study locations
NCT04005976: Recruiting study of Aortic Aneurysm and Aortic Dissection, sponsored by The University of Texas Health Science Center, Houston.
NCT04005976 is a study of Aortic Aneurysm and Aortic Dissection that is actively recruiting participants, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 5,000 participants, above the 283-participant average among 14 other Aortic Aneurysm trials with a reported enrollment target (1667% higher). The trial reports 20 study locations across 16 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04005976, a study of Aortic Aneurysm and Aortic Dissection, is actively recruiting participants, sponsored by The University of Texas Health Science Center, Houston.
- RECRUITING
- Registry status
- 5,000 participants
- Enrollment target
- 20
- Study locations
Study Summary
The Montalcino Aortic Consortium (MAC) will provide the infrastructure to assemble large cohorts of patients with mutations in known heritable thoracic aortic disease (H-TAD) genes, define the phenotype associated with these genes, and determine genetic and environmental modifiers of H-TAD.
Primary Outcome
Aortic Dissection
Conditions Studied
Study Locations (20)
California
- HOAG memorial hospital presbyterian - Newport Beach
- Hoag Memorial Hospital Presbyterian - Newport Beach
- Sutter Health - Sacramento
Texas
- Baylor College of Medicine - Houston
- Texas Children's Hospital - Houston
- The University of Texas Health Science Center at Houston - Houston
Kentucky
- University of Kentucky - Lexington
Massachusetts
- Massachusetts General Hospital - Boston
Michigan
- University of Michigan - Ann Arbor
Missouri
- Washington University in St. Louis - St Louis
Nebraska
- University of Nebraska Medical Center - Omaha
New York
- St. Francis Hospital (Catholic Health) - Roslyn
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5,000 participants |
| Start Date | 2016-06-15 |
| Est. Completion | 2037-01-01 |
What NCT04005976 shows while recruiting
NCT04005976 is an observational study that tracks outcomes without assigning an intervention. Its 5,000 participants enrollment target places it among the larger protocols in the corpus, above the 283-participant average among 14 other Aortic Aneurysm trials with a reported enrollment target (1667% higher).
The record links to 3 conditions, with Aortic Aneurysm appearing as the primary indexed condition, and to 0 interventions.
NCT04005976 names 20 study sites across 16 states, led by California, Texas, Kentucky.
Frequently Asked Questions
What is clinical trial NCT04005976 about?
NCT04005976 is a clinical study titled "Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease". The Montalcino Aortic Consortium (MAC) will provide the infrastructure to assemble large cohorts of patients with mutations in known heritable thoracic aortic disease (H-TAD) genes, define the phenotype associated with these genes, and determine genetic and environmental modifiers of H-TAD.
What is the current status of trial NCT04005976?
This trial is currently recruiting. The enrollment target is 5,000 participants. The study started on 2016-06-15. Estimated completion is 2037-01-01.
What conditions does trial NCT04005976 study?
This clinical trial studies the following conditions: Aortic Aneurysm, Aortic Dissection, Aortic Diseases.
Who is sponsoring clinical trial NCT04005976?
This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04005976 being conducted?
This trial has 20 study locations across California, Kentucky, Massachusetts, Michigan, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Aortic Aneurysm
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04005976's enrollment target sits among peer trials
5,000 1st of 14 higher than 14 of 14 other Aortic Aneurysm trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aortic Aneurysm trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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