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NCT04000659 · ClinicalTrials.gov registry record · NA
Episealer® Knee System IDE Clinical Study
A NA study of Degenerative Lesion of Articular Cartilage of Knee, sponsored by Episurf Medical.
- Active
- Registry status
- NA
- Development phase
- 13
- Enrollment target
- 13
- Study locations
NCT04000659: Active NA study of Degenerative Lesion of Articular Cartilage of Knee, sponsored by Episurf Medical.
NCT04000659 is a NA study of Degenerative Lesion of Articular Cartilage of Knee that is active but no longer recruiting, run by Episurf Medical. The registered enrollment target is 13 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). The trial reports 13 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04000659, a NA study of Degenerative Lesion of Articular Cartilage of Knee, is active but no longer recruiting, sponsored by Episurf Medical.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 13 participants
- Enrollment target
- 13
- Study locations
Study Summary
The study is a randomized, prospective, multicenter, controlled clinical trial of the Episealer Knee System. The Episealer Knee System is intended for subjects with up to two focal femoral knee chondral or osteochondral lesion that is causing pain and/or disability and requires surgical treatment.
Primary Outcome
This endpoint will examine the change in KOOS subscores at 24 months
Conditions Studied
Interventions
- PROCEDURE Microfracture
- DEVICE Episealer Knee System
Study Locations (13)
Other
- Universitatsmedizin Berlin Charite - Berlin
- Orthocentrum Hamburg - Hamburg
Arizona
- Physicians Research Group - Tempe
California
- Horizon Clinical Research - La Mesa
Louisiana
- Ochsner Sports Medicine Institute - New Orleans
New Jersey
- Hackensack University Medical Center - Hackensack
New York
- Plancher Orthopaedics & Sports Medicine - New York
Ohio
- Ohio State University - Columbus
Tennessee
- Helios Clinical Research - Jackson
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2020-06-18 |
| Est. Completion | 2028-06 |
| Phase | NA |
What the registry record for NCT04000659 still lists
NCT04000659 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Degenerative Lesion of Articular Cartilage of Knee appearing as the primary indexed condition, and to 2 interventions - of which Microfracture is the first listed.
NCT04000659 lists 13 locations in 12 states (Other, Arizona, California).
Frequently Asked Questions
What is clinical trial NCT04000659 about?
NCT04000659 is a clinical study titled "Episealer® Knee System IDE Clinical Study". The study is a randomized, prospective, multicenter, controlled clinical trial of the Episealer Knee System. The Episealer Knee System is intended for subjects with up to two focal femoral knee chondral or osteochondral lesion that is causing pain and/or disability and requires surgical treatment.
What is the current status of trial NCT04000659?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 13 participants. The study started on 2020-06-18. Estimated completion is 2028-06.
What conditions does trial NCT04000659 study?
This clinical trial studies the following conditions: Degenerative Lesion of Articular Cartilage of Knee.
What interventions are being tested in trial NCT04000659?
The interventions under investigation include: Microfracture (PROCEDURE), Episealer Knee System (DEVICE).
Who is sponsoring clinical trial NCT04000659?
This trial is sponsored by Episurf Medical, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04000659 being conducted?
This trial has 13 study locations across Arizona, California, Louisiana, New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04000659's enrollment target sits among peer trials
13 1911th of 2000 higher than 88 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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