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NCT03990545 · ClinicalTrials.gov registry record

Vessel Wall MR Imaging to Explore Sex-Differences of Intracranial Arterial Wall Changes After Suspected Stroke

A clinical trial, sponsored by University of Pennsylvania.

Completed
Registry status
11
Enrollment target

NCT03990545: Completed study, sponsored by University of Pennsylvania.

NCT03990545 is a clinical trial that has completed, run by University of Pennsylvania. The registered enrollment target is 11 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03990545 has completed, sponsored by University of Pennsylvania.

COMPLETED
Registry status
11 participants
Enrollment target

Study Summary

Despite advances in stroke care, women continue to face worse outcomes after stroke than men. This disparity in outcomes may be related to biologic sex-differences that manifest in the development and progression of atherosclerosis. Decades of cyclic changes in the hormonal milieu lead to different metabolic profiles in women. These changes may also explain sex-differences in risk factor profiles of atherogenesis and plaque composition. The investigators' objective is to conduct a cross-sectional MR imaging study of suspected stroke patients to compare the burden and composition of intracranial atherosclerosis and risk factors between men and women. Results from this study are expected to show that sex and sex-specific risk factors should be considered at the outset of stroke evaluation for risk-stratification. In the era of precision medicine, the investigators propose the role of sex should be a starting point in the clinical evaluation of stroke.

Primary Outcome

Vessel wall imaging characteristics on multicontrast MR imaging

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2019-06-12
Est. Completion 2021-03-05
University of Pennsylvania

1,423 total trials

What the finished NCT03990545 record still lists

NCT03990545 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 11 participants, a relatively small participant target.

The record links to 0 conditions, and to 0 interventions.

NCT03990545 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03990545 about?

NCT03990545 is a clinical study titled "Vessel Wall MR Imaging to Explore Sex-Differences of Intracranial Arterial Wall Changes After Suspected Stroke". Despite advances in stroke care, women continue to face worse outcomes after stroke than men. This disparity in outcomes may be related to biologic sex-differences that manifest in the development and progression of atherosclerosis. Decades of cyclic changes in the hormonal milieu lead to different ...

What is the current status of trial NCT03990545?

This trial is currently completed. The enrollment target is 11 participants. The study started on 2019-06-12. Estimated completion is 2021-03-05.

Who is sponsoring clinical trial NCT03990545?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT03990545, the US trial registry maintained by the National Library of Medicine. NCT03990545 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.