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NCT03981055 · ClinicalTrials.gov registry record · NA
Parkinson's Disease: Enhancing Physical Therapy With Brain Stimulation for Treating Postural Instability.
A NA study of Parkinson Disease, sponsored by Spaulding Rehabilitation Hospital.
- Active
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT03981055: Active NA study of Parkinson Disease, sponsored by Spaulding Rehabilitation Hospital.
NCT03981055 is a NA study of Parkinson Disease that is active but no longer recruiting, run by Spaulding Rehabilitation Hospital. The registered enrollment target is 40 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03981055, a NA study of Parkinson Disease, is active but no longer recruiting, sponsored by Spaulding Rehabilitation Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This trial aims to understand the mechanism and to test whether transcranial direct current stimulation (tDCS) combined with transcranial ultrasound (TUS) (tDCS+TUS) combined with physical therapy (PT) will induce significant therapeutic effects in postural instability in Parkinson's disease (PT) patients. The investigators designed a double-blinded, placebo controlled, randomized study to investigate the effects of 2 weeks of TDCS+TUS on postural instability in PD patients receiving PT. (Followed by biweekly sessions for 2 more weeks in Phase II)
Primary Outcome
Motor function was assessed using the Unified Parkinson's Disease Rating Scale (UPDRS) Part III - Motor Examination, which measures tremor, rigidity, bradykinesia, postural instability, and gait. Scores range from 0 to 108, where higher scores indicate worse motor impairment (i.e., lower scores represent better motor function).
Conditions Studied
Interventions
- OTHER Physical Therapy
- DEVICE Active Comparator: Active tDCS and Active TUS
- DEVICE Sham Comparator: Sham TDCS and Sham TUS
Study Locations (1)
Massachusetts
- Spaulding Rehabilitation Network Research Institute - Charlestown
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2020-01-23 |
| Est. Completion | 2026-10-30 |
| Phase | NA |
What the registry record for NCT03981055 still lists
NCT03981055 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Parkinson Disease appearing as the primary indexed condition, and to 3 interventions - of which Physical Therapy is the first listed.
NCT03981055 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT03981055 about?
NCT03981055 is a clinical study titled "Parkinson's Disease: Enhancing Physical Therapy With Brain Stimulation for Treating Postural Instability.". This trial aims to understand the mechanism and to test whether transcranial direct current stimulation (tDCS) combined with transcranial ultrasound (TUS) (tDCS+TUS) combined with physical therapy (PT) will induce significant therapeutic effects in postural instability in Parkinson's disease (PT) pa...
What is the current status of trial NCT03981055?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2020-01-23. Estimated completion is 2026-10-30.
What conditions does trial NCT03981055 study?
This clinical trial studies the following conditions: Parkinson Disease.
What interventions are being tested in trial NCT03981055?
The interventions under investigation include: Physical Therapy (OTHER), Active Comparator: Active tDCS and Active TUS (DEVICE), Sham Comparator: Sham TDCS and Sham TUS (DEVICE).
Who is sponsoring clinical trial NCT03981055?
This trial is sponsored by Spaulding Rehabilitation Hospital, which has 101 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03981055 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Parkinson Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03981055's enrollment target sits among peer trials
40 173rd of 297 higher than 109 of 297 other Parkinson Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinson Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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