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NCT03976102 · ClinicalTrials.gov registry record · Phase 3

Compare Efficacy, Safety, and Immunogenicity of Proposed Rituximab Biosimilar (DRL_RI) With MabThera® in LTB Follicular Lymphoma

A Phase 3 study, sponsored by Dr. Reddy's Laboratories Limited.

Completed
Registry status
Phase 3
Development phase
317
Enrollment target

NCT03976102 is a Phase 3 study that has completed, run by Dr. Reddy's Laboratories Limited. The registered enrollment target is 317 participants.

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The verdict

NCT03976102, a Phase 3 study, has completed, sponsored by Dr. Reddy's Laboratories Limited.

COMPLETED
Registry status
Phase 3
Development phase
317 participants
Enrollment target

Study Summary

The primary objective of the current study is to demonstrate the equivalent efficacy of rituximab (DRL\_RI) and MabThera® in subjects with Low Tumor Burden Follicular Lymphoma (LTB-FL). Also evaluated by Pharmacokinetic, safety, and immunogenicity assessment between a proposed biosimilar (DRL\_RI) and the RMP, as an component of clinical study program, and collectively providing the evidence of biosimilarity. The study will compare the safety and efficacy of DRL\_RI vs MabThera in patients with Low Tumor Burden Follicular Lymphoma (LTB-FL). The primary objective is to establish comparative efficacy as measured by ORR up to week 28

Interventions

  • BIOLOGICAL DRL_RI (Proposed rituximab biosimilar)
  • OTHER MabThera®

Trial Details

FieldValue
Enrollment Target 317 participants
Start Date 2019-05-15
Est. Completion 2023-02-27
Phase Phase 3

Sponsor

Dr. Reddy's Laboratories Limited

52 total trials

What the Registry Record Tells You About NCT03976102

The ClinicalTrials.gov registry entry for NCT03976102 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 317 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Dr. Reddy's Laboratories Limited, which has 52 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which DRL_RI (Proposed rituximab biosimilar) is the first listed.

NCT03976102 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03976102 about?

NCT03976102 is a clinical study titled "Compare Efficacy, Safety, and Immunogenicity of Proposed Rituximab Biosimilar (DRL_RI) With MabThera® in LTB Follicular Lymphoma". The primary objective of the current study is to demonstrate the equivalent efficacy of rituximab (DRL\_RI) and MabThera® in subjects with Low Tumor Burden Follicular Lymphoma (LTB-FL). Also evaluated by Pharmacokinetic, safety, and immunogenicity assessment between a proposed biosimilar (DRL\_RI) ...

What is the current status of trial NCT03976102?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 317 participants. The study started on 2019-05-15. Estimated completion is 2023-02-27.

What interventions are being tested in trial NCT03976102?

The interventions under investigation include: DRL_RI (Proposed rituximab biosimilar) (BIOLOGICAL), MabThera® (OTHER).

Who is sponsoring clinical trial NCT03976102?

This trial is sponsored by Dr. Reddy's Laboratories Limited, which has 52 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.