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NCT03958474 · ClinicalTrials.gov registry record · Early Phase 1

Neurobehavioral Mechanisms of Choice in Opioid Use Disorder

A Early Phase 1 study, sponsored by Joshua A. Lile, Ph.D..

Completed
Registry status
Early Phase 1
Development phase
12
Enrollment target

NCT03958474 is a Early Phase 1 study that has completed, run by Joshua A. Lile, Ph.D.. The registered enrollment target is 12 participants.

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The verdict

NCT03958474, a Early Phase 1 study, has completed, sponsored by Joshua A. Lile, Ph.D..

COMPLETED
Registry status
Early Phase 1
Development phase
12 participants
Enrollment target

Study Summary

The objective of this protocol is to use probabilistic reinforcement learning choice tasks and magnetic resonance neuroimaging to demonstrate the impact of problematic opioid use and opioid withdrawal on dynamic decision-making and reveal the neurobehavioral and neurobiological processes underlying abnormal task performance. A second objective is to identify an appropriate dose of intravenous remifentanil for subsequent studies in physically dependent individuals with opioid use disorder.

Interventions

  • DRUG Oxycodone

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2019-08-16
Est. Completion 2025-07-10
Phase Early Phase 1

Sponsor

Joshua A. Lile, Ph.D.

7 total trials

What the Registry Record Tells You About NCT03958474

The ClinicalTrials.gov registry entry for NCT03958474 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Joshua A. Lile, Ph.D., which has 7 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Oxycodone is the first listed.

NCT03958474 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03958474 about?

NCT03958474 is a clinical study titled "Neurobehavioral Mechanisms of Choice in Opioid Use Disorder". The objective of this protocol is to use probabilistic reinforcement learning choice tasks and magnetic resonance neuroimaging to demonstrate the impact of problematic opioid use and opioid withdrawal on dynamic decision-making and reveal the neurobehavioral and neurobiological processes underlying ...

What is the current status of trial NCT03958474?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 12 participants. The study started on 2019-08-16. Estimated completion is 2025-07-10.

What interventions are being tested in trial NCT03958474?

The interventions under investigation include: Oxycodone (DRUG).

Who is sponsoring clinical trial NCT03958474?

This trial is sponsored by Joshua A. Lile, Ph.D., which has 7 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.