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NCT03952884 · ClinicalTrials.gov registry record · NA

Skeletal Muscle Protein Synthetic Response to Amino Acid and Peptides

A NA study of Protein Metabolism, sponsored by University of Illinois at Urbana-Champaign.

Completed
Registry status
NA
Development phase
10
Enrollment target
1
Study location

NCT03952884 is a NA study of Protein Metabolism that has completed, run by University of Illinois at Urbana-Champaign. The registered enrollment target is 10 participants, below the 50-participant average among 5 other Protein Metabolism trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03952884, a NA study of Protein Metabolism, has completed, sponsored by University of Illinois at Urbana-Champaign.

COMPLETED
Registry status
NA
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

Skeletal muscle quality is an important determinant of exercise performance and overall health. It is vital for not just movement, but also metabolizing nutrients. Protein from the diet can promote muscle protein synthesis for muscle recovery and growth. More importantly, doing so shifts net protein balance positively (e.g. protein synthesis is greater than protein breakdown) and promotes greater rates of muscle protein turnover. Leucine is an amino acid required to build muscle, but it also acts as a signaling molecule informing the muscle to start protein synthesis. Before reaching skeletal muscle, dietary protein is digested into small peptides and free amino acids. Rate of absorption from the intestine to the blood stream is significantly faster for peptides compared to amino acids. As amino acid availability in the blood is a precursor for muscle protein synthesis, our objective is to determine if the different absorption rates between free amino acid and peptides influence muscle protein synthetic and breakdown rates.

Conditions Studied

Interventions

  • BEHAVIORAL Resistance Exercise
  • DIETARY_SUPPLEMENT Leucine
  • BEHAVIORAL No Resistance Exercise
  • DIETARY_SUPPLEMENT Dileucine

Study Locations (1)

Illinois

  • Freer Hall - Urbana

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2019-05-03
Est. Completion 2019-11-20
Phase NA

What the Registry Record Tells You About NCT03952884

The ClinicalTrials.gov registry entry for NCT03952884 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 50-participant average among 5 other Protein Metabolism trials with a reported enrollment target (80% lower). The listed sponsor is University of Illinois at Urbana-Champaign, which has 129 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Protein Metabolism appearing as the primary indexed condition, and to 4 interventions - of which Resistance Exercise is the first listed.

NCT03952884 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT03952884 about?

NCT03952884 is a clinical study titled "Skeletal Muscle Protein Synthetic Response to Amino Acid and Peptides". Skeletal muscle quality is an important determinant of exercise performance and overall health. It is vital for not just movement, but also metabolizing nutrients. Protein from the diet can promote muscle protein synthesis for muscle recovery and growth. More importantly, doing so shifts net protein...

What is the current status of trial NCT03952884?

This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2019-05-03. Estimated completion is 2019-11-20.

What conditions does trial NCT03952884 study?

This clinical trial studies the following conditions: Protein Metabolism.

What interventions are being tested in trial NCT03952884?

The interventions under investigation include: Resistance Exercise (BEHAVIORAL), Leucine (DIETARY_SUPPLEMENT), No Resistance Exercise (BEHAVIORAL), Dileucine (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT03952884?

This trial is sponsored by University of Illinois at Urbana-Champaign, which has 129 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03952884 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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