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NCT03943537 · ClinicalTrials.gov registry record · Phase 2
Effects of Intranasal Insulin on Neuroimaging Markers and Cognition in Patients With Psychotic Disorders
A Phase 2 study, sponsored by Mclean Hospital.
- Completed
- Registry status
- Phase 2
- Development phase
- 87
- Enrollment target
NCT03943537: Completed Phase 2 study, sponsored by Mclean Hospital.
NCT03943537 is a Phase 2 study that has completed, run by Mclean Hospital. The registered enrollment target is 87 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (35% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03943537, a Phase 2 study, has completed, sponsored by Mclean Hospital.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 87 participants
- Enrollment target
Study Summary
This clinical trial is a single center, single dose study of the acute effects of intranasal insulin on energy metabolism and cognitive function in patients with schizophrenia, schizoaffective and bipolar disorders, compared and healthy controls.
Primary Outcome
Changes in brain NAD+/NADH ratio as measured by in vivo 31P magnetic resonance spectroscopy
Interventions
- DRUG Intranasal Insulin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 87 participants |
| Start Date | 2019-10-01 |
| Est. Completion | 2024-02-23 |
| Phase | Phase 2 |
What the finished NCT03943537 record still lists
NCT03943537 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 87 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (35% lower).
The record links to 0 conditions, and to 1 intervention - of which Intranasal Insulin is the first listed.
NCT03943537 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03943537 about?
NCT03943537 is a clinical study titled "Effects of Intranasal Insulin on Neuroimaging Markers and Cognition in Patients With Psychotic Disorders". This clinical trial is a single center, single dose study of the acute effects of intranasal insulin on energy metabolism and cognitive function in patients with schizophrenia, schizoaffective and bipolar disorders, compared and healthy controls.
What is the current status of trial NCT03943537?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 87 participants. The study started on 2019-10-01. Estimated completion is 2024-02-23.
What interventions are being tested in trial NCT03943537?
The interventions under investigation include: Intranasal Insulin (DRUG).
Who is sponsoring clinical trial NCT03943537?
This trial is sponsored by Mclean Hospital, which has 140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03943537's enrollment target sits among peer trials
87 810th of 2000 higher than 1,189 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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