Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03934710 · ClinicalTrials.gov registry record · Phase 1
Mood Effects of Serotonin Agonists Extended
A Phase 1 study, sponsored by University of Chicago.
- Completed
- Registry status
- Phase 1
- Development phase
- 56
- Enrollment target
NCT03934710: Completed Phase 1 study, sponsored by University of Chicago.
NCT03934710 is a Phase 1 study that has completed, run by University of Chicago. The registered enrollment target is 56 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03934710, a Phase 1 study, has completed, sponsored by University of Chicago.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 56 participants
- Enrollment target
Study Summary
In this study we are examining the effects of repeated very low doses of serotonin agonists on mood individuals with negative mood.
Primary Outcome
The primary outcome measure is the depression anxiety and stress scale (DASS) 21. This self-report measure contains 21 items and the range of scores for depression is 0-42, anxiety 0-42, and stress 0-42. Our primary outcome measure is total depression scale ratings during session 5, with lower scores indicating lower ratings of depression.
Interventions
- DRUG Placebo
- DRUG Serotonin agonist - 13ug
- DRUG Serotonin agonist - 26ug
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2019-04-20 |
| Est. Completion | 2021-06-07 |
| Phase | Phase 1 |
What the finished NCT03934710 record still lists
NCT03934710 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT03934710 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03934710 about?
NCT03934710 is a clinical study titled "Mood Effects of Serotonin Agonists Extended". In this study we are examining the effects of repeated very low doses of serotonin agonists on mood individuals with negative mood.
What is the current status of trial NCT03934710?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 56 participants. The study started on 2019-04-20. Estimated completion is 2021-06-07.
What interventions are being tested in trial NCT03934710?
The interventions under investigation include: Placebo (DRUG), Serotonin agonist - 13ug (DRUG), Serotonin agonist - 26ug (DRUG).
Who is sponsoring clinical trial NCT03934710?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03934710's enrollment target sits among peer trials
56 902nd of 2000 higher than 1,083 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02287428 · 56 participants · Phase 1
Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM
- NCT02923011 · 56 participants · Phase 3
Comparative Effectiveness of MRgFUS Versus CTgRFA for Osteoid Osteomas
- NCT02935283 · 56 participants
Neuroimaging and Neuropsychological Outcomes in Urea Cycle Disorders
- NCT03375866 · 56 participants · NA
Effects of Mixed Nut Consumption on Satiety and Weight Management
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI