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NCT03931941 · ClinicalTrials.gov registry record · Phase 3

Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCH CD3-OLS)

A Phase 3 study, sponsored by Rebiotix.

Completed
Registry status
Phase 3
Development phase
793
Enrollment target

NCT03931941 is a Phase 3 study that has completed, run by Rebiotix. The registered enrollment target is 793 participants.

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The verdict

NCT03931941, a Phase 3 study, has completed, sponsored by Rebiotix.

COMPLETED
Registry status
Phase 3
Development phase
793 participants
Enrollment target

Study Summary

This is a prospective, multicenter, open-label Phase 3 study of a microbiota suspension of intestinal microbes. Patients who have had at least one recurrence of CDI after a primary episode and have completed at least one round of standard-of-care oral antibiotic therapy or have had at least two episodes of severe CDI resulting in hospitalization may be eligible for the study. Subjects may receive a second RBX2660 enema if they are deemed treatment failures following the initial enema per the protocol-specified treatment failure definition.

Interventions

  • DRUG RBX2660

Trial Details

FieldValue
Enrollment Target 793 participants
Start Date 2019-07-30
Est. Completion 2023-07-21
Phase Phase 3

Sponsor

Rebiotix

5 total trials

What the Registry Record Tells You About NCT03931941

The ClinicalTrials.gov registry entry for NCT03931941 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 793 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Rebiotix, which has 5 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which RBX2660 is the first listed.

NCT03931941 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03931941 about?

NCT03931941 is a clinical study titled "Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCH CD3-OLS)". This is a prospective, multicenter, open-label Phase 3 study of a microbiota suspension of intestinal microbes. Patients who have had at least one recurrence of CDI after a primary episode and have completed at least one round of standard-of-care oral antibiotic therapy or have had at least two epis...

What is the current status of trial NCT03931941?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 793 participants. The study started on 2019-07-30. Estimated completion is 2023-07-21.

What interventions are being tested in trial NCT03931941?

The interventions under investigation include: RBX2660 (DRUG).

Who is sponsoring clinical trial NCT03931941?

This trial is sponsored by Rebiotix, which has 5 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.