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NCT06208150 · ClinicalTrials.gov registry record · Phase 3
A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide
A Phase 3 study of Multiple Myeloma, sponsored by Janssen Research & Development.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 795
- Enrollment target
- 20
- Study locations
NCT06208150: Recruiting Phase 3 study of Multiple Myeloma, sponsored by Janssen Research & Development.
NCT06208150 is a Phase 3 study of Multiple Myeloma that is actively recruiting participants, run by Janssen Research & Development. The registered enrollment target is 795 participants, above the 545-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (46% higher). The trial reports 20 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06208150, a Phase 3 study of Multiple Myeloma, is actively recruiting participants, sponsored by Janssen Research & Development.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 795 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to compare the effectiveness of either talquetamab plus pomalidomide (Tal-P) or talquetamab plus teclistamab (Tal-Tec) with elotuzumab, pomalidomide, and dexamethasone (EPd) or pomalidomide, bortezomib, and dexamethasone (PVd).
Primary Outcome
PFS is defined as the duration from the date of randomization to either progressive disease or death, whichever comes first.
Conditions Studied
Interventions
- DRUG Teclistamab
- DRUG Dexamethasone
- DRUG Pomalidomide
- DRUG Talquetamab
- DRUG Elotuzumab
Study Locations (20)
Maryland
- Luminis Health Center for Cancer and Blood Disorders - Annapolis
- University of Maryland School of Medicine - Baltimore
- The Sidney Kimmel Comprehensive Cancer Center at John Hopkins - Baltimore
Michigan
- University of Michigan - Ann Arbor
- Henry Ford Cancer Institute - Detroit
- Henry Ford Health Providence Southfield Hospital - Southfield
California
- UCSF Fresno - Clovis
- UCLA - Santa Monica
Florida
- Memorial Healthcare System - Hollywood
- Moffitt Cancer Center - Tampa
Georgia
- Winship Cancer Institute Emory University - Atlanta
- City of Hope Cancer Center - Newnan
Connecticut
- Yale University School Of Medicine - New Haven
Delaware
- Medical Oncology Hematology Consultants, PA - Newark
Idaho
- Kootenai Health - Coeur d'Alene
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 795 participants |
| Start Date | 2024-01-22 |
| Est. Completion | 2028-03-31 |
| Phase | Phase 3 |
What NCT06208150 shows while recruiting
NCT06208150 is an interventional study that assigns participants to a tested intervention. The registered 795 participants enrollment target is mid-sized for trials with a published cap, above the 545-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (46% higher).
The record links to 1 condition, with Multiple Myeloma appearing as the primary indexed condition, and to 5 interventions - of which Teclistamab is the first listed.
NCT06208150 names 20 study sites across 13 states, led by Maryland, Michigan, California.
Frequently Asked Questions
What is clinical trial NCT06208150 about?
NCT06208150 is a clinical study titled "A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide". The purpose of this study is to compare the effectiveness of either talquetamab plus pomalidomide (Tal-P) or talquetamab plus teclistamab (Tal-Tec) with elotuzumab, pomalidomide, and dexamethasone (EPd) or pomalidomide, bortezomib, and dexamethasone (PVd).
What is the current status of trial NCT06208150?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 795 participants. The study started on 2024-01-22. Estimated completion is 2028-03-31.
What conditions does trial NCT06208150 study?
This clinical trial studies the following conditions: Multiple Myeloma.
What interventions are being tested in trial NCT06208150?
The interventions under investigation include: Teclistamab (DRUG), Dexamethasone (DRUG), Pomalidomide (DRUG), Talquetamab (DRUG), Elotuzumab (DRUG).
Who is sponsoring clinical trial NCT06208150?
This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06208150 being conducted?
This trial has 20 study locations across California, Connecticut, Delaware, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Multiple Myeloma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06208150's enrollment target sits among peer trials
795 29th of 438 higher than 410 of 438 other Multiple Myeloma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Multiple Myeloma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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