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NCT03911050 · ClinicalTrials.gov registry record · NA
Scavenging of Reactive Carbonyl Species by Apple Polyphenols in Human
A NA study, sponsored by North Carolina Agriculture & Technical State University.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
NCT03911050: Completed NA study, sponsored by North Carolina Agriculture & Technical State University.
NCT03911050 is a NA study that has completed, run by North Carolina Agriculture & Technical State University. The registered enrollment target is 12 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03911050, a NA study, has completed, sponsored by North Carolina Agriculture & Technical State University.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
Study Summary
This is an interventional study to investigate formation and pharmacokinetics of reactive carbonyl species adducts of apple polyphenols in human after a single dose of apple consumption.
Primary Outcome
Urinary excretion rates of major reactive carbonyl species (RCS) conjugates were determined using LC-MS analysis. Urine samples were enzymatically hydrolyzed. Chromatographic separation of RCS-polyphenols (PPs) in human urine was performed on a Gemini column (50 mm × 2.0 mm; i.d. 3 μm) using a Dionex HPLC. Targeted conjugates were identified using an LTQ Velos Pro ion trap mass spectrometer equipped with an electrospray ionization (ESI) source operating in negative ion mode. Quantitation for RCS
Interventions
- DIETARY_SUPPLEMENT Apple consumption
- DIETARY_SUPPLEMENT Control group
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2018-11-26 |
| Est. Completion | 2018-12-21 |
| Phase | NA |
What the finished NCT03911050 record still lists
NCT03911050 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Apple consumption is the first listed.
NCT03911050 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03911050 about?
NCT03911050 is a clinical study titled "Scavenging of Reactive Carbonyl Species by Apple Polyphenols in Human". This is an interventional study to investigate formation and pharmacokinetics of reactive carbonyl species adducts of apple polyphenols in human after a single dose of apple consumption.
What is the current status of trial NCT03911050?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2018-11-26. Estimated completion is 2018-12-21.
What interventions are being tested in trial NCT03911050?
The interventions under investigation include: Apple consumption (DIETARY_SUPPLEMENT), Control group (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT03911050?
This trial is sponsored by North Carolina Agriculture & Technical State University, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03911050's enrollment target sits among peer trials
12 1913th of 2000 higher than 74 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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