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NCT03909607 · ClinicalTrials.gov registry record · Phase 4

Nebulized Sub-dissociative Dose Ketamine for Treating Pain

A Phase 4 study, sponsored by Antonios Likourezos.

Completed
Registry status
Phase 4
Development phase
120
Enrollment target

NCT03909607 is a Phase 4 study that has completed, run by Antonios Likourezos. The registered enrollment target is 120 participants.

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The verdict

NCT03909607, a Phase 4 study, has completed, sponsored by Antonios Likourezos.

COMPLETED
Registry status
Phase 4
Development phase
120 participants
Enrollment target

Study Summary

The investigators previous research study comparing the efficacy of intravenous ketamine to morphine showed ketamine to provide equivalent relief of moderate to severe acute pain in emergency department patients. A second study by the investigators showed that increasing the time of administration of the ketamine, from a push injection to a drip infusion, will minimize the adverse effects experienced by recipients of ketamine. The investigators now aim to see if nebulized subdissociative-dose ketamine administered as a single agent in a dose of 1.5 mg/kg via Breath-Actuated Nebulizers (BAN) over 5-15 minutes will provide a better pain relief in comparison to 1 mg/kg and 0.75 mg/kg doses or if the lower doses are equally as effective.

Interventions

  • DRUG Ketamine 0.75 mg/kg
  • DRUG Ketamine 1.0 mg/kg
  • DRUG Ketamine 1.5 mg/kg

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2019-04-16
Est. Completion 2021-06-30
Phase Phase 4

Sponsor

Antonios Likourezos

33 total trials

What the Registry Record Tells You About NCT03909607

The ClinicalTrials.gov registry entry for NCT03909607 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Antonios Likourezos, which has 33 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Ketamine 0.75 mg/kg is the first listed.

NCT03909607 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03909607 about?

NCT03909607 is a clinical study titled "Nebulized Sub-dissociative Dose Ketamine for Treating Pain". The investigators previous research study comparing the efficacy of intravenous ketamine to morphine showed ketamine to provide equivalent relief of moderate to severe acute pain in emergency department patients. A second study by the investigators showed that increasing the time of administration o...

What is the current status of trial NCT03909607?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 120 participants. The study started on 2019-04-16. Estimated completion is 2021-06-30.

What interventions are being tested in trial NCT03909607?

The interventions under investigation include: Ketamine 0.75 mg/kg (DRUG), Ketamine 1.0 mg/kg (DRUG), Ketamine 1.5 mg/kg (DRUG).

Who is sponsoring clinical trial NCT03909607?

This trial is sponsored by Antonios Likourezos, which has 33 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.