Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03891667 · ClinicalTrials.gov registry record · Phase 1
Disulfiram: A Test of Symptom Reduction Among Patients With Previously Treated Lyme Disease
A Phase 1 study, sponsored by Research Foundation for Mental Hygiene.
- Completed
- Registry status
- Phase 1
- Development phase
- 11
- Enrollment target
NCT03891667 is a Phase 1 study that has completed, run by Research Foundation for Mental Hygiene. The registered enrollment target is 11 participants.
The verdict
NCT03891667, a Phase 1 study, has completed, sponsored by Research Foundation for Mental Hygiene.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 11 participants
- Enrollment target
Study Summary
Approximately 10-20% of patients experience ongoing symptoms despite having received standard antibiotic therapy for Lyme disease. Possible explanations for persistent symptoms include persistent infection and/or post-infectious causes. Recent in vitro studies indicate that disulfiram is effective at killing both the actively replicating and the more quiescent persister forms of Borrelia burgdorferi, the microbe that causes Lyme Disease. In this study, the investigators are examining the safety of disulfiram among patients with post-treatment Lyme disease symptoms. The investigators are also conducting a preliminary investigation regarding the relative benefit of 4 vs 8 weeks of treatment with disulfiram.
Interventions
- DRUG Disulfiram
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2019-07-31 |
| Est. Completion | 2022-03-31 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03891667
The ClinicalTrials.gov registry entry for NCT03891667 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Research Foundation for Mental Hygiene, which has 27 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Disulfiram is the first listed.
NCT03891667 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03891667 about?
NCT03891667 is a clinical study titled "Disulfiram: A Test of Symptom Reduction Among Patients With Previously Treated Lyme Disease". Approximately 10-20% of patients experience ongoing symptoms despite having received standard antibiotic therapy for Lyme disease. Possible explanations for persistent symptoms include persistent infection and/or post-infectious causes. Recent in vitro studies indicate that disulfiram is effective a...
What is the current status of trial NCT03891667?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 11 participants. The study started on 2019-07-31. Estimated completion is 2022-03-31.
What interventions are being tested in trial NCT03891667?
The interventions under investigation include: Disulfiram (DRUG).
Who is sponsoring clinical trial NCT03891667?
This trial is sponsored by Research Foundation for Mental Hygiene, which has 27 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.