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NCT03851406 · ClinicalTrials.gov registry record · NA
Woodsmoke Particulate + Hypertonic Saline
A NA study, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- NA
- Development phase
- 9
- Enrollment target
NCT03851406 is a NA study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 9 participants.
The verdict
NCT03851406, a NA study, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- NA
- Development phase
- 9 participants
- Enrollment target
Study Summary
Deployment of military personnel has been associated with increased respiratory illness likely due, in part, to inhalation of unusual particulate matter (PM), such as from burn pits. Inflammation is a key initial response to inhaled particulates. The investigator has developed a protocol using inhaled wood smoke particles (WSP) as a way to study PM-induced airway inflammation. Exposure to wood smoke particles causes symptoms, even in healthy people, such as eye irritation, cough, shortness of breath, and increased mucous production. The purpose of this research study is to see if a single treatment of inhaled hypertonic saline (HS) can diminish this PM-induced airway inflammation by rapidly clearing the WSP inhaled particles from airway surfaces. The exposure will be 500 ug/m³ of WSP for 2 hours, with intermittent exercise on a bicycle and rest. The wood is burned in a typical wood stove and piped into the chamber.
Interventions
- OTHER No treatment
- DEVICE 5% Hypertonic Saline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2019-08-01 |
| Est. Completion | 2024-09-12 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03851406
The ClinicalTrials.gov registry entry for NCT03851406 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 9 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which No treatment is the first listed.
NCT03851406 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03851406 about?
NCT03851406 is a clinical study titled "Woodsmoke Particulate + Hypertonic Saline". Deployment of military personnel has been associated with increased respiratory illness likely due, in part, to inhalation of unusual particulate matter (PM), such as from burn pits. Inflammation is a key initial response to inhaled particulates. The investigator has developed a protocol using inhal...
What is the current status of trial NCT03851406?
This trial is currently completed. It is a NA study. The enrollment target is 9 participants. The study started on 2019-08-01. Estimated completion is 2024-09-12.
What interventions are being tested in trial NCT03851406?
The interventions under investigation include: No treatment (OTHER), 5% Hypertonic Saline (DEVICE).
Who is sponsoring clinical trial NCT03851406?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
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