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NCT03848754 · ClinicalTrials.gov registry record · Phase 1

Pracinostat and Gemtuzumab Ozogamicin (PraGO) in Patients With Relapsed/Refractory Acute Myeloid Leukemia

A Phase 1 study, sponsored by Medical College of Wisconsin.

Completed
Registry status
Phase 1
Development phase
14
Enrollment target

NCT03848754 is a Phase 1 study that has completed, run by Medical College of Wisconsin. The registered enrollment target is 14 participants.

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The verdict

NCT03848754, a Phase 1 study, has completed, sponsored by Medical College of Wisconsin.

COMPLETED
Registry status
Phase 1
Development phase
14 participants
Enrollment target

Study Summary

This is a prospective, single-center phase 1 clinical study aimed at determining the maximum-tolerated dose and safety of the combination of gemtuzumab ozogamicin (GO) and pracinostat (P) in patients with relapsed/refractory acute myeloid leukemia.

Interventions

  • DRUG Gemtuzumab Ozogamicin 3 mg/m^2
  • DRUG Gemtuzumab Ozogamicin 2 mg/m^2
  • DRUG Pracinostat - 45 mg
  • DRUG Pracinostat - 60 mg

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2019-05-24
Est. Completion 2021-05-05
Phase Phase 1

Sponsor

Medical College of Wisconsin

447 total trials

What the Registry Record Tells You About NCT03848754

The ClinicalTrials.gov registry entry for NCT03848754 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medical College of Wisconsin, which has 447 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Gemtuzumab Ozogamicin 3 mg/m^2 is the first listed.

NCT03848754 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03848754 about?

NCT03848754 is a clinical study titled "Pracinostat and Gemtuzumab Ozogamicin (PraGO) in Patients With Relapsed/Refractory Acute Myeloid Leukemia". This is a prospective, single-center phase 1 clinical study aimed at determining the maximum-tolerated dose and safety of the combination of gemtuzumab ozogamicin (GO) and pracinostat (P) in patients with relapsed/refractory acute myeloid leukemia.

What is the current status of trial NCT03848754?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 14 participants. The study started on 2019-05-24. Estimated completion is 2021-05-05.

What interventions are being tested in trial NCT03848754?

The interventions under investigation include: Gemtuzumab Ozogamicin 3 mg/m^2 (DRUG), Gemtuzumab Ozogamicin 2 mg/m^2 (DRUG), Pracinostat - 45 mg (DRUG), Pracinostat - 60 mg (DRUG).

Who is sponsoring clinical trial NCT03848754?

This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.