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NCT03840486 · ClinicalTrials.gov registry record · Phase 4
Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements
A Phase 4 study of Rapid Sequence Intubation, sponsored by Emory University.
- Completed
- Registry status
- Phase 4
- Development phase
- 105
- Enrollment target
- 2
- Study locations
NCT03840486: Completed Phase 4 study of Rapid Sequence Intubation, sponsored by Emory University.
NCT03840486 is a Phase 4 study of Rapid Sequence Intubation that has completed, run by Emory University. The registered enrollment target is 105 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (80% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03840486, a Phase 4 study of Rapid Sequence Intubation, has completed, sponsored by Emory University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 105 participants
- Enrollment target
- 2
- Study locations
Study Summary
This study examines the performance of a nasal cannula end-tidal oxygen (EtO2) measurement as compared to the gold standard of single breath end-tidal oxygen measurements in healthy volunteers. The purpose of this study is to examine the ability of each sensor to predict oxygen levels in real time.
Primary Outcome
Real-time end-tidal oxygen measurements as measured with a nasal cannula (NC) and single-breath (SB) end-tidal oxygen measurements across increasing oxygen concentrations and flow rates for the non-invasive ventilation (NIV) and non-rebreather mask (NRBM) study arms.
Conditions Studied
Interventions
- DEVICE Non-rebreather mask (NRBM)
- DEVICE Non-invasive ventilator mask (NIV)
- DEVICE Nasal cannula EtO2 sensor
- DRUG Oxygen (NRBM)
- DRUG Oxygen (NIV)
Study Locations (2)
Georgia
- Grady Memorial Hospital - Atlanta
- Emory University Hospital Midtown - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 105 participants |
| Start Date | 2019-09-24 |
| Est. Completion | 2023-10-20 |
| Phase | Phase 4 |
What the finished NCT03840486 record still lists
NCT03840486 is an interventional study that assigns participants to a tested intervention. The registered 105 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (80% lower).
The record links to 1 condition, with Rapid Sequence Intubation appearing as the primary indexed condition, and to 5 interventions - of which Non-rebreather mask (NRBM) is the first listed.
NCT03840486 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT03840486 about?
NCT03840486 is a clinical study titled "Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements". This study examines the performance of a nasal cannula end-tidal oxygen (EtO2) measurement as compared to the gold standard of single breath end-tidal oxygen measurements in healthy volunteers. The purpose of this study is to examine the ability of each sensor to predict oxygen levels in real time.
What is the current status of trial NCT03840486?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 105 participants. The study started on 2019-09-24. Estimated completion is 2023-10-20.
What conditions does trial NCT03840486 study?
This clinical trial studies the following conditions: Rapid Sequence Intubation.
What interventions are being tested in trial NCT03840486?
The interventions under investigation include: Non-rebreather mask (NRBM) (DEVICE), Non-invasive ventilator mask (NIV) (DEVICE), Nasal cannula EtO2 sensor (DEVICE), Oxygen (NRBM) (DRUG), Oxygen (NIV) (DRUG).
Who is sponsoring clinical trial NCT03840486?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03840486 being conducted?
This trial has 2 study locations across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03840486's enrollment target sits among peer trials
105 749th of 2000 higher than 1,248 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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