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NCT03832114 · ClinicalTrials.gov registry record · Phase 2
Study on Efficacy and Safety of LNP023 in C3 Glomerulopathy Patients Transplanted and Not Transplanted
A Phase 2 study, sponsored by Novartis Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 27
- Enrollment target
NCT03832114: Completed Phase 2 study, sponsored by Novartis Pharmaceuticals.
NCT03832114 is a Phase 2 study that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 27 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03832114, a Phase 2 study, has completed, sponsored by Novartis Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 27 participants
- Enrollment target
Study Summary
The study is an open-label, two cohort non-randomized study evaluating the efficacy, safety, and pharmacokinetics of LNP023 in patients with C3G (Cohort A) and patients who have undergone kidney transplant and have C3G recurrence (Cohort B).
Primary Outcome
Change in proteinuria assessed by ratio to baseline of UPCR derived from 24h urine collection
Interventions
- DRUG LNP023
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2019-02-20 |
| Est. Completion | 2021-04-23 |
| Phase | Phase 2 |
What the finished NCT03832114 record still lists
NCT03832114 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 1 intervention - of which LNP023 is the first listed.
NCT03832114 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03832114 about?
NCT03832114 is a clinical study titled "Study on Efficacy and Safety of LNP023 in C3 Glomerulopathy Patients Transplanted and Not Transplanted". The study is an open-label, two cohort non-randomized study evaluating the efficacy, safety, and pharmacokinetics of LNP023 in patients with C3G (Cohort A) and patients who have undergone kidney transplant and have C3G recurrence (Cohort B).
What is the current status of trial NCT03832114?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 27 participants. The study started on 2019-02-20. Estimated completion is 2021-04-23.
What interventions are being tested in trial NCT03832114?
The interventions under investigation include: LNP023 (DRUG).
Who is sponsoring clinical trial NCT03832114?
This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03832114's enrollment target sits among peer trials
27 1697th of 2000 higher than 293 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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