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NCT03810703 · ClinicalTrials.gov registry record · Phase 1
Differential Responses to Drugs and Sweet Tastes
A Phase 1 study, sponsored by University of Chicago.
- Completed
- Registry status
- Phase 1
- Development phase
- 93
- Enrollment target
NCT03810703 is a Phase 1 study that has completed, run by University of Chicago. The registered enrollment target is 93 participants.
The verdict
NCT03810703, a Phase 1 study, has completed, sponsored by University of Chicago.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 93 participants
- Enrollment target
Study Summary
Young adults who exhibit "bipolar phenotype" (BPP), defined as occasional episodes of mood elevation and heightened activity, are at risk for several psychiatric disorders, including problem use of drugs and alcohol. Mood elevation has been linked to higher alcohol consumption and alcohol use disorders. Individuals with BPP show elevated lifetime prevalence of alcohol use disorders (between 39%-61%), figures that exceed those reported in both major depression and schizophrenia. Recently, the investigators demonstrated in a controlled laboratory study that individuals with BPP (but not meeting criteria for full Bipolar I Disorder), report dampened responses to a single dose of alcohol, compared to placebo. In the current study, the investigators seek to extend these findings to determine if young adults reporting BPP, based on a questionnaire, will exhibit reduced responses to other rewarding stimuli, such as d-amphetamine and sweet tastes. The investigators hypothesize that the BPP individuals will exhibit dampened subjective responses to stimulant and sweet taste rewards compared to healthy controls.
Interventions
- DRUG Placebo oral capsule
- DRUG d-amphetamine 10 mg oral capsule
- DRUG d-amphetamine 20 mg oral capsule
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 93 participants |
| Start Date | 2017-02-09 |
| Est. Completion | 2018-08-09 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03810703
The ClinicalTrials.gov registry entry for NCT03810703 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 93 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Chicago, which has 796 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Placebo oral capsule is the first listed.
NCT03810703 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03810703 about?
NCT03810703 is a clinical study titled "Differential Responses to Drugs and Sweet Tastes". Young adults who exhibit "bipolar phenotype" (BPP), defined as occasional episodes of mood elevation and heightened activity, are at risk for several psychiatric disorders, including problem use of drugs and alcohol. Mood elevation has been linked to higher alcohol consumption and alcohol use disord...
What is the current status of trial NCT03810703?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 93 participants. The study started on 2017-02-09. Estimated completion is 2018-08-09.
What interventions are being tested in trial NCT03810703?
The interventions under investigation include: Placebo oral capsule (DRUG), d-amphetamine 10 mg oral capsule (DRUG), d-amphetamine 20 mg oral capsule (DRUG).
Who is sponsoring clinical trial NCT03810703?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
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