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NCT03783195 · ClinicalTrials.gov registry record · NA
Genetic-specific Effects of Fructose on Liver Lipogenesis
A NA study, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- NA
- Development phase
- 15
- Enrollment target
NCT03783195: Completed NA study, sponsored by University of North Carolina, Chapel Hill.
NCT03783195 is a NA study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03783195, a NA study, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
Study Summary
The primary goal of this study is to identify a set of genotypes that increase the risk for nonalcoholic fatty liver disease (NAFLD) and predispose individuals to increased de novo lipogenesis (DNL) and liver fat accumulation when exposed to fructose intake. The proposed goal will be achieved through the completion of following aims: 1. To determine the impact of prolonged exposure of fructose on hepatic lipid accumulation in Caucasian individuals with high and low genetic risk for NAFLD, 2. to determine the impact of acute exposure of fructose on hepatic DNL, and 3. to determine the relationship between markers of DNL, liver fat accumulation and serum concentrations of lipids, uric acid and liver function markers before and after the fructose challenge.
Primary Outcome
Elastography (Fibroscan) will be used to measure changes in liver fat.
Interventions
- OTHER Sugar drink
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2019-01-25 |
| Est. Completion | 2023-04-25 |
| Phase | NA |
What the finished NCT03783195 record still lists
NCT03783195 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Sugar drink is the first listed.
NCT03783195 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03783195 about?
NCT03783195 is a clinical study titled "Genetic-specific Effects of Fructose on Liver Lipogenesis". The primary goal of this study is to identify a set of genotypes that increase the risk for nonalcoholic fatty liver disease (NAFLD) and predispose individuals to increased de novo lipogenesis (DNL) and liver fat accumulation when exposed to fructose intake. The proposed goal will be achieved throug...
What is the current status of trial NCT03783195?
This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2019-01-25. Estimated completion is 2023-04-25.
What interventions are being tested in trial NCT03783195?
The interventions under investigation include: Sugar drink (OTHER).
Who is sponsoring clinical trial NCT03783195?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03783195's enrollment target sits among peer trials
15 1881st of 2000 higher than 92 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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