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NCT03783195 · ClinicalTrials.gov registry record · NA

Genetic-specific Effects of Fructose on Liver Lipogenesis

A NA study, sponsored by University of North Carolina, Chapel Hill.

Completed
Registry status
NA
Development phase
15
Enrollment target

NCT03783195 is a NA study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 15 participants.

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The verdict

NCT03783195, a NA study, has completed, sponsored by University of North Carolina, Chapel Hill.

COMPLETED
Registry status
NA
Development phase
15 participants
Enrollment target

Study Summary

The primary goal of this study is to identify a set of genotypes that increase the risk for nonalcoholic fatty liver disease (NAFLD) and predispose individuals to increased de novo lipogenesis (DNL) and liver fat accumulation when exposed to fructose intake. The proposed goal will be achieved through the completion of following aims: 1. To determine the impact of prolonged exposure of fructose on hepatic lipid accumulation in Caucasian individuals with high and low genetic risk for NAFLD, 2. to determine the impact of acute exposure of fructose on hepatic DNL, and 3. to determine the relationship between markers of DNL, liver fat accumulation and serum concentrations of lipids, uric acid and liver function markers before and after the fructose challenge.

Interventions

  • OTHER Sugar drink

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2019-01-25
Est. Completion 2023-04-25
Phase NA

What the Registry Record Tells You About NCT03783195

The ClinicalTrials.gov registry entry for NCT03783195 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Sugar drink is the first listed.

NCT03783195 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03783195 about?

NCT03783195 is a clinical study titled "Genetic-specific Effects of Fructose on Liver Lipogenesis". The primary goal of this study is to identify a set of genotypes that increase the risk for nonalcoholic fatty liver disease (NAFLD) and predispose individuals to increased de novo lipogenesis (DNL) and liver fat accumulation when exposed to fructose intake. The proposed goal will be achieved throug...

What is the current status of trial NCT03783195?

This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2019-01-25. Estimated completion is 2023-04-25.

What interventions are being tested in trial NCT03783195?

The interventions under investigation include: Sugar drink (OTHER).

Who is sponsoring clinical trial NCT03783195?

This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.