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NCT03771157 · ClinicalTrials.gov registry record · Early Phase 1

Serologic Response to SHINGRIX Vaccine in Patients With CLL and WM Treated With BTK Inhibitors

A Early Phase 1 study of Chronic Lymphocytic Leukemia (CLL) and Waldenstrom Macroglobulinemia (WM), sponsored by University of Rochester.

Completed
Registry status
Early Phase 1
Development phase
33
Enrollment target
1
Study location

NCT03771157 is a Early Phase 1 study of Chronic Lymphocytic Leukemia (CLL) and Waldenstrom Macroglobulinemia (WM) that has completed, run by University of Rochester. The registered enrollment target is 33 participants, below the 190-participant average among 29 other Chronic Lymphocytic Leukemia (CLL) trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03771157, a Early Phase 1 study of Chronic Lymphocytic Leukemia (CLL) and Waldenstrom Macroglobulinemia (WM), has completed, sponsored by University of Rochester.

COMPLETED
Registry status
Early Phase 1
Development phase
33 participants
Enrollment target
1
Study location

Study Summary

The primary objective of the study is to assess the capability of a patient with Chronic Lymphocytic Leukemia (CLL) or Waldenström Macroglobulinemia (WM) to generate an immune response to the Shingrix vaccine under first-line BTK inhibitors.

Interventions

  • DRUG Shingrix vaccine

Study Locations (1)

New York

  • University of Rochester - Rochester

Trial Details

FieldValue
Enrollment Target 33 participants
Start Date 2019-02-01
Est. Completion 2022-08-03
Phase Early Phase 1

Sponsor

University of Rochester

636 total trials

What the Registry Record Tells You About NCT03771157

The ClinicalTrials.gov registry entry for NCT03771157 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 33 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 190-participant average among 29 other Chronic Lymphocytic Leukemia (CLL) trials with a reported enrollment target (83% lower). The listed sponsor is University of Rochester, which has 636 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Chronic Lymphocytic Leukemia (CLL) appearing as the primary indexed condition, and to 1 intervention - of which Shingrix vaccine is the first listed.

NCT03771157 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT03771157 about?

NCT03771157 is a clinical study titled "Serologic Response to SHINGRIX Vaccine in Patients With CLL and WM Treated With BTK Inhibitors". The primary objective of the study is to assess the capability of a patient with Chronic Lymphocytic Leukemia (CLL) or Waldenström Macroglobulinemia (WM) to generate an immune response to the Shingrix vaccine under first-line BTK inhibitors.

What is the current status of trial NCT03771157?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 33 participants. The study started on 2019-02-01. Estimated completion is 2022-08-03.

What conditions does trial NCT03771157 study?

This clinical trial studies the following conditions: Chronic Lymphocytic Leukemia (CLL), Waldenstrom Macroglobulinemia (WM).

What interventions are being tested in trial NCT03771157?

The interventions under investigation include: Shingrix vaccine (DRUG).

Who is sponsoring clinical trial NCT03771157?

This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03771157 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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