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NCT03734640 · ClinicalTrials.gov registry record · NA
Optimal Post Tpa-Iv Monitoring in Ischemic Stroke
A NA study of Acute Ischemic Stroke Patients Receiving Reperfusion Therapy, sponsored by Craig Anderson.
- Completed
- Registry status
- NA
- Development phase
- 4,922
- Enrollment target
- 20
- Study locations
NCT03734640: Completed NA study of Acute Ischemic Stroke Patients Receiving Reperfusion Therapy, sponsored by Craig Anderson.
NCT03734640 is a NA study of Acute Ischemic Stroke Patients Receiving Reperfusion Therapy that has completed, run by Craig Anderson. The registered enrollment target is 4,922 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (251% higher). The trial reports 20 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03734640, a NA study of Acute Ischemic Stroke Patients Receiving Reperfusion Therapy, has completed, sponsored by Craig Anderson.
- COMPLETED
- Registry status
- NA
- Development phase
- 4,922 participants
- Enrollment target
- 20
- Study locations
Study Summary
OPTIMISTmain is an investigator-initiated and conducted, international, multicentre, stepped wedge cluster randomized controlled trial comparing the effects of different intensities of nursing care monitoring for patients with acute ischemic stroke of mild severity and without critical care needs after IV-tPA.
Primary Outcome
Physical function measured according to a 7 level categorical scale, where 0-1 indicates no or minimal symptoms, 2-5 indicates increasing levels of disability/dependencey, and 6=death
Conditions Studied
Interventions
- OTHER Low-intensity monitoring strategy
- OTHER Guideline recommended standard monitoring
Study Locations (20)
Maryland
- University of Maryland Medical Center - Baltimore
- The John Hopkins Hospital - Baltimore
- Howard County General Hospital - Columbia
Missouri
- SSM Health DePaul Hospital - Bridgeton
- Saint Luke's Hospital of Kansas City - Kansas City
- Research Medical Center - Kansas City
Colorado
- Centura St. Anthony Hospital - Lakewood
- Centura Littleton Adventist Hospital - Littleton
Michigan
- Henry Ford Health System - Detroit
- Ascension Providence Hospital - Novi
Pennsylvania
- Lehigh Valley Health Network - Allentown
- Penn State Health - Hershey
Massachusetts
- University of Massachusetts Worcester - Worcester
Nevada
- Renown Health - Reno
New York
- University of Rochester Medical Center - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4,922 participants |
| Start Date | 2021-04-28 |
| Est. Completion | 2025-01-23 |
| Phase | NA |
What the finished NCT03734640 record still lists
NCT03734640 is an interventional study that assigns participants to a tested intervention. Its 4,922 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (251% higher).
The record links to 1 condition, with Acute Ischemic Stroke Patients Receiving Reperfusion Therapy appearing as the primary indexed condition, and to 2 interventions - of which Low-intensity monitoring strategy is the first listed.
NCT03734640 names 20 study sites across 13 states, led by Maryland, Missouri, Colorado.
Frequently Asked Questions
What is clinical trial NCT03734640 about?
NCT03734640 is a clinical study titled "Optimal Post Tpa-Iv Monitoring in Ischemic Stroke". OPTIMISTmain is an investigator-initiated and conducted, international, multicentre, stepped wedge cluster randomized controlled trial comparing the effects of different intensities of nursing care monitoring for patients with acute ischemic stroke of mild severity and without critical care needs af...
What is the current status of trial NCT03734640?
This trial is currently completed. It is a NA study. The enrollment target is 4,922 participants. The study started on 2021-04-28. Estimated completion is 2025-01-23.
What conditions does trial NCT03734640 study?
This clinical trial studies the following conditions: Acute Ischemic Stroke Patients Receiving Reperfusion Therapy.
What interventions are being tested in trial NCT03734640?
The interventions under investigation include: Low-intensity monitoring strategy (OTHER), Guideline recommended standard monitoring (OTHER).
Who is sponsoring clinical trial NCT03734640?
This trial is sponsored by Craig Anderson, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03734640 being conducted?
This trial has 20 study locations across Colorado, Maryland, Massachusetts, Michigan, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03734640's enrollment target sits among peer trials
4,922 28th of 2000 higher than 1,973 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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