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NCT03733444 · ClinicalTrials.gov registry record · Phase 3

A Clinical Study to Test How Effective and Safe GLPG1690 is for Participants With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care

A Phase 3 study, sponsored by Lakefront Biotherapeutics.

Terminated
Registry status
Phase 3
Development phase
781
Enrollment target

NCT03733444: Clinical Trial Phase 3 study, sponsored by Lakefront Biotherapeutics.

NCT03733444 is a Phase 3 study that was terminated before completion, run by Lakefront Biotherapeutics. The registered enrollment target is 781 participants, roughly in line with the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03733444, a Phase 3 study, was terminated before completion, sponsored by Lakefront Biotherapeutics.

TERMINATED
Registry status
Phase 3
Development phase
781 participants
Enrollment target

Study Summary

The main purpose of this study was to see how GLPG1690 works together with the current standard treatment on your lung function and IPF disease in general. The study also investigated how well GLPG1690 is tolerated (for example if you get any side effects while on study drug).

Primary Outcome

FVC (in mL) is the maximum amount of air exhaled from lungs by a participant after taking their deepest possible breath, as measured by spirometry.

Interventions

  • DRUG Placebo
  • DRUG GLPG1690

Trial Details

FieldValue
Enrollment Target 781 participants
Start Date 2018-11-05
Est. Completion 2021-03-30
Phase Phase 3
Lakefront Biotherapeutics

15 total trials

Why NCT03733444 stopped before completion

NCT03733444 is an interventional study that assigns participants to a tested intervention. The registered 781 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT03733444 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03733444 about?

NCT03733444 is a clinical study titled "A Clinical Study to Test How Effective and Safe GLPG1690 is for Participants With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care". The main purpose of this study was to see how GLPG1690 works together with the current standard treatment on your lung function and IPF disease in general. The study also investigated how well GLPG1690 is tolerated (for example if you get any side effects while on study drug).

What is the current status of trial NCT03733444?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 781 participants. The study started on 2018-11-05. Estimated completion is 2021-03-30.

What interventions are being tested in trial NCT03733444?

The interventions under investigation include: Placebo (DRUG), GLPG1690 (DRUG).

Who is sponsoring clinical trial NCT03733444?

This trial is sponsored by Lakefront Biotherapeutics, which has 15 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03733444's enrollment target sits among peer trials

781 434th of 2000 higher than 1,567 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03733444, the US trial registry maintained by the National Library of Medicine. NCT03733444 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.