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NCT03732352 · ClinicalTrials.gov registry record · Phase 2

18F-FDG PET and Osimertinib in Evaluating Glucose Utilization in Patients with EGFR Activated Recurrent Glioblastoma

A Phase 2 study, sponsored by Jonsson Comprehensive Cancer Center.

Completed
Registry status
Phase 2
Development phase
12
Enrollment target

NCT03732352 is a Phase 2 study that has completed, run by Jonsson Comprehensive Cancer Center. The registered enrollment target is 12 participants.

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The verdict

NCT03732352, a Phase 2 study, has completed, sponsored by Jonsson Comprehensive Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
12 participants
Enrollment target

Study Summary

This phase II trial studies how well fludeoxyglucose F-18 (18F-FDG) positron emission tomography (PET) and osimertinib works in evaluating glucose utilization in patients with EGFR activated glioblastoma. Osimertinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. 18F-FDG PET imaging may help to detect changes in tumor glucose utilization, which may allow investigators to obtain an early read out on the impact of osimertinib on recurrent glioblastoma patients whose tumors have EGFR activation.

Interventions

  • DRUG Osimertinib
  • PROCEDURE Positron Emission Tomography
  • OTHER Fludeoxyglucose F-18

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2018-11-28
Est. Completion 2024-01-31
Phase Phase 2

Sponsor

Jonsson Comprehensive Cancer Center

321 total trials

What the Registry Record Tells You About NCT03732352

The ClinicalTrials.gov registry entry for NCT03732352 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Jonsson Comprehensive Cancer Center, which has 321 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Osimertinib is the first listed.

NCT03732352 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03732352 about?

NCT03732352 is a clinical study titled "18F-FDG PET and Osimertinib in Evaluating Glucose Utilization in Patients with EGFR Activated Recurrent Glioblastoma". This phase II trial studies how well fludeoxyglucose F-18 (18F-FDG) positron emission tomography (PET) and osimertinib works in evaluating glucose utilization in patients with EGFR activated glioblastoma. Osimertinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell ...

What is the current status of trial NCT03732352?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2018-11-28. Estimated completion is 2024-01-31.

What interventions are being tested in trial NCT03732352?

The interventions under investigation include: Osimertinib (DRUG), Positron Emission Tomography (PROCEDURE), Fludeoxyglucose F-18 (OTHER).

Who is sponsoring clinical trial NCT03732352?

This trial is sponsored by Jonsson Comprehensive Cancer Center, which has 321 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.