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NCT03705585 · ClinicalTrials.gov registry record · Phase 4
CVD 38000: Study of Responses to Vaccination With Typhoid and/or Cholera
A Phase 4 study of Typhoid and/or Cholera Vaccination, sponsored by University of Maryland, Baltimore.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 240
- Enrollment target
- 1
- Study location
NCT03705585: Recruiting Phase 4 study of Typhoid and/or Cholera Vaccination, sponsored by University of Maryland, Baltimore.
NCT03705585 is a Phase 4 study of Typhoid and/or Cholera Vaccination that is actively recruiting participants, run by University of Maryland, Baltimore. The registered enrollment target is 240 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03705585, a Phase 4 study of Typhoid and/or Cholera Vaccination, is actively recruiting participants, sponsored by University of Maryland, Baltimore.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 240 participants
- Enrollment target
- 1
- Study location
Study Summary
This is an open-label, non-randomized study. The purpose of this study is to better understand how vaccines against typhoid fever and cholera affect the normal immune system and bacteria in the intestine. Patients having standard-of-care endoscopies (colonoscopy and/or esophagogastroduodenoscopy (EGD)) will be divided into 3 groups: Group 1: Vivotif typhoid vaccination and/or Vaxchora cholera vaccination then endoscopy Group 2: Endoscopy, then Vivotif typhoid vaccination and/or Vaxchora cholera vaccination, then follow-up endoscopy Group 3: Endoscopy without vaccination. Both vaccines used in this study are licensed by the Food and Drug Administration (FDA) for travelers to developing countries. Volunteers will be asked to donate tissue, blood, saliva and stool samples for studying how the body responds to the typhoid and/or cholera vaccine.
Conditions Studied
Interventions
- DRUG Vivotif Typhoid Oral Vaccine
- DRUG Vaxchora
Study Locations (1)
Maryland
- University of Maryland, Baltimore, Center for Vaccine Development and Global Health - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 240 participants |
| Start Date | 2018-11-05 |
| Est. Completion | 2029-05-31 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03705585
The ClinicalTrials.gov registry entry for NCT03705585 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 240 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Maryland, Baltimore, which has 560 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Typhoid and/or Cholera Vaccination appearing as the primary indexed condition, and to 2 interventions - of which Vivotif Typhoid Oral Vaccine is the first listed.
NCT03705585 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT03705585 about?
NCT03705585 is a clinical study titled "CVD 38000: Study of Responses to Vaccination With Typhoid and/or Cholera". This is an open-label, non-randomized study. The purpose of this study is to better understand how vaccines against typhoid fever and cholera affect the normal immune system and bacteria in the intestine. Patients having standard-of-care endoscopies (colonoscopy and/or esophagogastroduodenoscopy (EG...
What is the current status of trial NCT03705585?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 240 participants. The study started on 2018-11-05. Estimated completion is 2029-05-31.
What conditions does trial NCT03705585 study?
This clinical trial studies the following conditions: Typhoid and/or Cholera Vaccination.
What interventions are being tested in trial NCT03705585?
The interventions under investigation include: Vivotif Typhoid Oral Vaccine (DRUG), Vaxchora (DRUG).
Who is sponsoring clinical trial NCT03705585?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03705585 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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