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NCT03703310 · ClinicalTrials.gov registry record · Phase 3

Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Subjects With Basal Cell Nevus Syndrome (Gorlin Syndrome)

A Phase 3 study, sponsored by Sol-Gel Technologies.

Completed
Registry status
Phase 3
Development phase
174
Enrollment target

NCT03703310: Completed Phase 3 study, sponsored by Sol-Gel Technologies.

NCT03703310 is a Phase 3 study that has completed, run by Sol-Gel Technologies. The registered enrollment target is 174 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03703310, a Phase 3 study, has completed, sponsored by Sol-Gel Technologies.

COMPLETED
Registry status
Phase 3
Development phase
174 participants
Enrollment target

Study Summary

This is a global, multicenter, randomized, double-blind, stratified, vehicle-controlled study of the efficacy and safety of Patidegib Topical Gel, 2%, applied topically twice daily to the face of adult participants with Gorlin syndrome. Participants will be required to apply the investigational product for 12 months. The primary endpoint is a comparison between the two treatment arms of the number of new BCCs that develop over the 12 month period.

Interventions

  • DRUG Patidegib Topical Gel, 2%
  • DRUG Patidegib Topical Gel, Vehicle

Trial Details

FieldValue
Enrollment Target 174 participants
Start Date 2019-02-19
Est. Completion 2020-12-28
Phase Phase 3
Sol-Gel Technologies

15 total trials

What the finished NCT03703310 record still lists

NCT03703310 is an interventional study that assigns participants to a tested intervention. The registered 174 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (77% lower).

The record links to 0 conditions, and to 2 interventions - of which Patidegib Topical Gel, 2% is the first listed.

NCT03703310 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03703310 about?

NCT03703310 is a clinical study titled "Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Subjects With Basal Cell Nevus Syndrome (Gorlin Syndrome)". This is a global, multicenter, randomized, double-blind, stratified, vehicle-controlled study of the efficacy and safety of Patidegib Topical Gel, 2%, applied topically twice daily to the face of adult participants with Gorlin syndrome. Participants will be required to apply the investigational prod...

What is the current status of trial NCT03703310?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 174 participants. The study started on 2019-02-19. Estimated completion is 2020-12-28.

What interventions are being tested in trial NCT03703310?

The interventions under investigation include: Patidegib Topical Gel, 2% (DRUG), Patidegib Topical Gel, Vehicle (DRUG).

Who is sponsoring clinical trial NCT03703310?

This trial is sponsored by Sol-Gel Technologies, which has 15 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03703310's enrollment target sits among peer trials

174 1442nd of 2000 higher than 556 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03703310, the US trial registry maintained by the National Library of Medicine. NCT03703310 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.