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NCT03700294 · ClinicalTrials.gov registry record · Phase 1

Safety, Tolerability, Pharmacokinetics, and Antitumor Study of ADCT-601 to Treat Advanced Solid Tumors

A Phase 1 study, sponsored by ADC Therapeutics S.A..

Terminated
Registry status
Phase 1
Development phase
18
Enrollment target

NCT03700294: Clinical Trial Phase 1 study, sponsored by ADC Therapeutics S.A..

NCT03700294 is a Phase 1 study that was terminated before completion, run by ADC Therapeutics S.A.. The registered enrollment target is 18 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03700294, a Phase 1 study, was terminated before completion, sponsored by ADC Therapeutics S.A..

TERMINATED
Registry status
Phase 1
Development phase
18 participants
Enrollment target

Study Summary

This study evaluates the safety, tolerance, pharmacokinetics (PK), and antitumor activity of ADCT-601 in patients with advanced solid tumors.

Primary Outcome

Frequency and severity of adverse events (AEs) and serious adverse events (SAEs)

Interventions

  • DRUG ADCT-601

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2018-12-21
Est. Completion 2019-12-11
Phase Phase 1
ADC Therapeutics S.A.

18 total trials

Why NCT03700294 stopped before completion

NCT03700294 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower).

The record links to 0 conditions, and to 1 intervention - of which ADCT-601 is the first listed.

NCT03700294 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03700294 about?

NCT03700294 is a clinical study titled "Safety, Tolerability, Pharmacokinetics, and Antitumor Study of ADCT-601 to Treat Advanced Solid Tumors". This study evaluates the safety, tolerance, pharmacokinetics (PK), and antitumor activity of ADCT-601 in patients with advanced solid tumors.

What is the current status of trial NCT03700294?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2018-12-21. Estimated completion is 2019-12-11.

What interventions are being tested in trial NCT03700294?

The interventions under investigation include: ADCT-601 (DRUG).

Who is sponsoring clinical trial NCT03700294?

This trial is sponsored by ADC Therapeutics S.A., which has 18 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03700294's enrollment target sits among peer trials

18 1720th of 2000 higher than 216 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03700294, the US trial registry maintained by the National Library of Medicine. NCT03700294 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.