Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Study to Evaluate the Effects of Fasinumab on Peripheral Nerve Function in Patients With Pain Due to Osteoarthritis of the Hip or Knee
NCT03691974 · View on ClinicalTrials.gov ↗
Study Summary
The primary objective of the study is to evaluate the effect of fasinumab compared to placebo on peripheral nerves in participants with pain due to Osteoarthritis (OA) of the hip or knee. The secondary objectives of the study are to: * Evaluate the efficacy of fasinumab compared to placebo in participants with pain due to OA of the hip or knee * Evaluate the safety and tolerability of fasinumab compared to placebo in participants with pain due to OA of the hip or knee * Characterize the concentrations of fasinumab in serum in participants with pain due to OA of the hip or knee * Evaluate the immunogenicity of fasinumab in participants with pain due to OA of the hip or knee.
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Fasinumab
Study Locations (20)
Florida
- Regeneron Study Site — Clearwater
- Regeneron Study Site — Jacksonville
- Regeneron Study Site — Miami
- Regeneron Study Site — Ocoee
- Regeneron Study Site — Orlando
Arizona
- Regeneron Study Site — Glendale
- Regeneron Study Site — Glendale
- Regeneron Study Site — Phoenix
- Regeneron Study Site — Tucson
Texas
- Regeneron Study Site — Bellaire
- Regeneron Study Site — Houston
- Regeneron Study Site — Houston
Illinois
- Regeneron Study Site — Chicago
- Regeneron Study Site — Chicago
Ohio
- Regeneron Study Site — Cincinnati
- Regeneron Study Site — Columbus
California
- Regeneron Study Site — Anaheim
Georgia
- Regeneron Study Site — Woodstock
Michigan
- Regeneron Study Site — Caro
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2018-10-15 |
| Est. Completion | 2021-01-07 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03691974
The ClinicalTrials.gov registry entry for NCT03691974 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 180 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Regeneron Pharmaceuticals, which has 290 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Osteoarthritis, Knee appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT03691974 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Florida, Arizona, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT03691974 about?
NCT03691974 is a clinical study titled "Study to Evaluate the Effects of Fasinumab on Peripheral Nerve Function in Patients With Pain Due to Osteoarthritis of the Hip or Knee". The primary objective of the study is to evaluate the effect of fasinumab compared to placebo on peripheral nerves in participants with pain due to Osteoarthritis (OA) of the hip or knee. The secondary objectives of the study are to: * Evaluate the efficacy of fasinumab compared to placebo in part...
What is the current status of trial NCT03691974?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 180 participants. The study started on 2018-10-15. Estimated completion is 2021-01-07.
What conditions does trial NCT03691974 study?
This clinical trial studies the following conditions: Osteoarthritis, Knee, Osteoarthritis, Hip. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT03691974?
The interventions under investigation include: Placebo (OTHER), Fasinumab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT03691974?
This trial is sponsored by Regeneron Pharmaceuticals, which has 290 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT03691974 being conducted?
This trial has 20 study locations across Arizona, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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