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NCT03688802 · ClinicalTrials.gov registry record · Phase 2
Efficacy of OC-01 Nasal Spray on Goblet Cell and Meibomian Gland Stimulation
A Phase 2 study, sponsored by Oyster Point Pharma.
- Completed
- Registry status
- Phase 2
- Development phase
- 18
- Enrollment target
NCT03688802: Completed Phase 2 study, sponsored by Oyster Point Pharma.
NCT03688802 is a Phase 2 study that has completed, run by Oyster Point Pharma. The registered enrollment target is 18 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03688802, a Phase 2 study, has completed, sponsored by Oyster Point Pharma.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 18 participants
- Enrollment target
Study Summary
The objective of this study is to evaluate the safety and effectiveness of OC-01 Nasal Spray as compared to placebo in simulating Goblet Cell and Meibomian Gland function in adult subjects with DED.
Primary Outcome
Mean change in Goblet Cell Area with a larger decrease is indicative of a better outcome.
Interventions
- DRUG OC-01 (varenicline) nasal spray
- DRUG Placebo (vehicle control) nasal spray
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2018-09-25 |
| Est. Completion | 2019-09-30 |
| Phase | Phase 2 |
What the finished NCT03688802 record still lists
NCT03688802 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower).
The record links to 0 conditions, and to 2 interventions - of which OC-01 (varenicline) nasal spray is the first listed.
NCT03688802 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03688802 about?
NCT03688802 is a clinical study titled "Efficacy of OC-01 Nasal Spray on Goblet Cell and Meibomian Gland Stimulation". The objective of this study is to evaluate the safety and effectiveness of OC-01 Nasal Spray as compared to placebo in simulating Goblet Cell and Meibomian Gland function in adult subjects with DED.
What is the current status of trial NCT03688802?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 18 participants. The study started on 2018-09-25. Estimated completion is 2019-09-30.
What interventions are being tested in trial NCT03688802?
The interventions under investigation include: OC-01 (varenicline) nasal spray (DRUG), Placebo (vehicle control) nasal spray (DRUG).
Who is sponsoring clinical trial NCT03688802?
This trial is sponsored by Oyster Point Pharma, which has 10 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03688802's enrollment target sits among peer trials
18 1898th of 2000 higher than 98 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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