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NCT03648840 · ClinicalTrials.gov registry record · NA
Human Alcohol Seeking Despite Aversion
A NA study, sponsored by Indiana University.
- Terminated
- Registry status
- NA
- Development phase
- 84
- Enrollment target
NCT03648840: Clinical Trial NA study, sponsored by Indiana University.
NCT03648840 is a NA study that was terminated before completion, run by Indiana University. The registered enrollment target is 84 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03648840, a NA study, was terminated before completion, sponsored by Indiana University.
- TERMINATED
- Registry status
- NA
- Development phase
- 84 participants
- Enrollment target
Study Summary
Prolonged alcohol use results in drinking despite resultant problems and adverse consequences. The investigators propose to test a laboratory model of human seeking despite aversion to use as an early marker of disease onset, and as a tool for study of its neural functional substrates, and identification of effective treatments.
Primary Outcome
Participants earn 2.5 min exposures to an increase in iv infusion rate (causing a prescribed increase in breath alcohol concentration (BRAC)) by completing repetitions of a constant attention button-pressing task (CAT). The task is designed so that the number of correct CAT trials required increases progressively from 1 (for the first drink) to 380 (for the 20th drink) on an accelerating scale. The dependent measure Breakpoint is defined as the cumulative number of correct and incorrect CAT tria
Interventions
- BEHAVIORAL Aversive Cue
- BEHAVIORAL Neutral Cue
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 84 participants |
| Start Date | 2018-04-04 |
| Est. Completion | 2022-05-04 |
| Phase | NA |
Why NCT03648840 stopped before completion
NCT03648840 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 2 interventions - of which Aversive Cue is the first listed.
NCT03648840 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03648840 about?
NCT03648840 is a clinical study titled "Human Alcohol Seeking Despite Aversion". Prolonged alcohol use results in drinking despite resultant problems and adverse consequences. The investigators propose to test a laboratory model of human seeking despite aversion to use as an early marker of disease onset, and as a tool for study of its neural functional substrates, and identific...
What is the current status of trial NCT03648840?
This trial is currently terminated. It is a NA study. The enrollment target is 84 participants. The study started on 2018-04-04. Estimated completion is 2022-05-04.
What interventions are being tested in trial NCT03648840?
The interventions under investigation include: Aversive Cue (BEHAVIORAL), Neutral Cue (BEHAVIORAL).
Who is sponsoring clinical trial NCT03648840?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03648840's enrollment target sits among peer trials
84 983rd of 2000 higher than 1,011 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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