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NCT03636451 · ClinicalTrials.gov registry record · Phase 3
Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage.o
A Phase 3 study, sponsored by University of California, San Diego.
- Completed
- Registry status
- Phase 3
- Development phase
- 114
- Enrollment target
NCT03636451: Completed Phase 3 study, sponsored by University of California, San Diego.
NCT03636451 is a Phase 3 study that has completed, run by University of California, San Diego. The registered enrollment target is 114 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03636451, a Phase 3 study, has completed, sponsored by University of California, San Diego.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 114 participants
- Enrollment target
Study Summary
The investigators are conducting a study on pain control for dilation and curettage (D\&C). Participants are eligible to enroll if they are a planning to have a D\&C in a participating clinic. The investigators are studying how different ratios of medication to liquid affect pain when injected around the cervix. Both potential methods use the same dose of medication, though researchers would like to know which one works better. To be in this study, participants must be over the age of 18 with an early pregnancy loss or undesired pregnancy measuring less than 12 weeks gestation undergoing D\&C while awake in clinic.
Primary Outcome
Distance (mm) from the left of the 100-mm Visual Analog Scale (VAS) (reflecting magnitude of pain) recorded at time of cervical dilation. Pain will be assessed using a 100 mm visual analogue scale with the anchors 0 = none, 100 mm = worst imaginable.
Interventions
- DRUG 40cc buffered 0.5% lidocaine with 2 units of vasopressin paracervical block
- DRUG 20cc 1% lidocaine with 2 units of vasopressin paracervical block
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 114 participants |
| Start Date | 2018-10-29 |
| Est. Completion | 2022-09-27 |
| Phase | Phase 3 |
What the finished NCT03636451 record still lists
NCT03636451 is an interventional study that assigns participants to a tested intervention. The registered 114 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 2 interventions - of which 40cc buffered 0.5% lidocaine with 2 units of vasopressin paracervical block is the first listed.
NCT03636451 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03636451 about?
NCT03636451 is a clinical study titled "Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage.o". The investigators are conducting a study on pain control for dilation and curettage (D\&C). Participants are eligible to enroll if they are a planning to have a D\&C in a participating clinic. The investigators are studying how different ratios of medication to liquid affect pain when injected aroun...
What is the current status of trial NCT03636451?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 114 participants. The study started on 2018-10-29. Estimated completion is 2022-09-27.
What interventions are being tested in trial NCT03636451?
The interventions under investigation include: 40cc buffered 0.5% lidocaine with 2 units of vasopressin paracervical block (DRUG), 20cc 1% lidocaine with 2 units of vasopressin paracervical block (DRUG).
Who is sponsoring clinical trial NCT03636451?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03636451's enrollment target sits among peer trials
114 1648th of 2000 higher than 350 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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