Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03626857 · ClinicalTrials.gov registry record · NA

MiACLR: Michigan Initiative for Anterior Cruciate Ligament Rehabilitation

A NA study, sponsored by University of Michigan.

Completed
Registry status
NA
Development phase
135
Enrollment target

NCT03626857: Completed NA study, sponsored by University of Michigan.

NCT03626857 is a NA study that has completed, run by University of Michigan. The registered enrollment target is 135 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03626857, a NA study, has completed, sponsored by University of Michigan.

COMPLETED
Registry status
NA
Development phase
135 participants
Enrollment target

Study Summary

This clinical trial evaluates interventions to maximize muscle function and improve cartilage health following anterior cruciate ligament reconstruction. Improving muscle function may improve patient outcomes, improve joint mechanics, and potentially serve as a prevention approach for post-traumatic knee osteoarthritis. Knee osteoarthritis (OA) is a disabling disease that carries a substantial burden to society and to the individual affected.

Primary Outcome

Bilateral concentric isokinetic muscle strength at 60 degrees per second. Limb symmetry index is calculated as (ACL strength/Non-ACL strength)\*100

Interventions

  • DEVICE Neuromuscular Electrical Stimulation (NMES)
  • OTHER Eccentric Exercise (ECC)
  • DEVICE Neuromuscular Electrical Stimulation (NMES) placebo
  • OTHER Eccentric Exercise (ECC) placebo

Trial Details

FieldValue
Enrollment Target 135 participants
Start Date 2019-02-22
Est. Completion 2025-01-09
Phase NA
University of Michigan

1,327 total trials

What the finished NCT03626857 record still lists

NCT03626857 is an interventional study that assigns participants to a tested intervention. The registered 135 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 4 interventions - of which Neuromuscular Electrical Stimulation (NMES) is the first listed.

NCT03626857 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03626857 about?

NCT03626857 is a clinical study titled "MiACLR: Michigan Initiative for Anterior Cruciate Ligament Rehabilitation". This clinical trial evaluates interventions to maximize muscle function and improve cartilage health following anterior cruciate ligament reconstruction. Improving muscle function may improve patient outcomes, improve joint mechanics, and potentially serve as a prevention approach for post-traumatic...

What is the current status of trial NCT03626857?

This trial is currently completed. It is a NA study. The enrollment target is 135 participants. The study started on 2019-02-22. Estimated completion is 2025-01-09.

What interventions are being tested in trial NCT03626857?

The interventions under investigation include: Neuromuscular Electrical Stimulation (NMES) (DEVICE), Eccentric Exercise (ECC) (OTHER), Neuromuscular Electrical Stimulation (NMES) placebo (DEVICE), Eccentric Exercise (ECC) placebo (OTHER).

Who is sponsoring clinical trial NCT03626857?

This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03626857's enrollment target sits among peer trials

135 726th of 2000 higher than 1,273 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00870129 · 135 participants · NA

    Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors

  • NCT03666000 · 135 participants · Phase 1

    Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

  • NCT04891510 · 135 participants · NA

    A Comparative Analysis of REVOLVE, LipoGrafter, and Viality in Autologous Fat Grafting During Breast Surgery

  • NCT05121051 · 135 participants · Phase 2

    Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03626857, the US trial registry maintained by the National Library of Medicine. NCT03626857 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.