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NCT03625986 · ClinicalTrials.gov registry record · NA
Does Switching to Nicotine Containing Electronic Cigarettes Reduce Health Risk Markers
A NA study, sponsored by Milton S. Hershey Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 105
- Enrollment target
NCT03625986: Completed NA study, sponsored by Milton S. Hershey Medical Center.
NCT03625986 is a NA study that has completed, run by Milton S. Hershey Medical Center. The registered enrollment target is 105 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03625986, a NA study, has completed, sponsored by Milton S. Hershey Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 105 participants
- Enrollment target
Study Summary
The overall goal of this project is to understand the likely health effects of cigarette smokers switching to a Standardized Research Electronic Cigarette (SREC) and to assess the role of nicotine delivery on switching and acceptability as well as markers of health outcomes. Current smokers who meet all eligibility criteria will completely switch from their combustible (regular) cigarettes to an electronic cigarette (SREC) that either contains 58 mg/ml of nicotine or 0 mg/ml of nicotine in the liquid. The investigators' hypothesis is that attempting to switch to a SREC will result in a reduction in markers of harms to health, as compared with the baseline (smoking) measures. The investigators also hypothesize that nicotine-containing SRECs will facilitate switching from smoking more efficiently than zero nicotine SRECs and will result in a significantly greater improvement in markers of health risk, but will result in higher ratings of dependence on the SREC (as compared to the zero nicotine SREC).
Primary Outcome
Concentration of urinary carcinogen biomarker of exposure, NNAL, corrected for creatinine
Interventions
- OTHER Nicotine-Containing Electronic Cigarette
- OTHER Non-Nicotine Electronic Cigarette
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 105 participants |
| Start Date | 2022-04-22 |
| Est. Completion | 2024-02-23 |
| Phase | NA |
What the finished NCT03625986 record still lists
NCT03625986 is an interventional study that assigns participants to a tested intervention. The registered 105 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 2 interventions - of which Nicotine-Containing Electronic Cigarette is the first listed.
NCT03625986 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03625986 about?
NCT03625986 is a clinical study titled "Does Switching to Nicotine Containing Electronic Cigarettes Reduce Health Risk Markers". The overall goal of this project is to understand the likely health effects of cigarette smokers switching to a Standardized Research Electronic Cigarette (SREC) and to assess the role of nicotine delivery on switching and acceptability as well as markers of health outcomes. Current smokers who mee...
What is the current status of trial NCT03625986?
This trial is currently completed. It is a NA study. The enrollment target is 105 participants. The study started on 2022-04-22. Estimated completion is 2024-02-23.
What interventions are being tested in trial NCT03625986?
The interventions under investigation include: Nicotine-Containing Electronic Cigarette (OTHER), Non-Nicotine Electronic Cigarette (OTHER).
Who is sponsoring clinical trial NCT03625986?
This trial is sponsored by Milton S. Hershey Medical Center, which has 396 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03625986's enrollment target sits among peer trials
105 834th of 2000 higher than 1,165 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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