Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03616587 · ClinicalTrials.gov registry record · Phase 1

Study of AZD9833 Alone or in Combination in Women With Advanced Breast Cancer.

A Phase 1 study of ER+ HER2- Advanced Breast Cancer, sponsored by AstraZeneca.

Active
Registry status
Phase 1
Development phase
396
Enrollment target
17
Study locations

NCT03616587 is a Phase 1 study of ER+ HER2- Advanced Breast Cancer that is active but no longer recruiting, run by AstraZeneca. The registered enrollment target is 396 participants. The trial reports 17 study locations across 6 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03616587, a Phase 1 study of ER+ HER2- Advanced Breast Cancer, is active but no longer recruiting, sponsored by AstraZeneca.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
396 participants
Enrollment target
17
Study locations

Study Summary

A Phase 1 Dose Escalation and Expansion Study of AZD9833 Alone or in Combination in Women with ER Positive, HER2 Negative Advanced Breast Cancer (SERENA-1)

Interventions

  • DRUG AZD9833
  • DRUG AZD9833 with palbociclib
  • DRUG AZD9833 with everolimus

Study Locations (17)

Other

  • Research Site - Barcelona
  • Research Site - Barcelona
  • Research Site - Madrid
  • Research Site - Madrid
  • Research Site - Seville
  • Research Site - Valencia
  • Research Site - Cambridge
  • Research Site - Leeds
  • Research Site - London
  • Research Site - Manchester
  • Research Site - Sutton
  • Research Site - Sutton

Colorado

  • Research Site - Aurora

Florida

  • Research Site - Sarasota

Pennsylvania

  • Research Site - Philadelphia

Tennessee

  • Research Site - Nashville

Utah

  • Research Site - Salt Lake City

Trial Details

FieldValue
Enrollment Target 396 participants
Start Date 2018-10-11
Est. Completion 2027-06-24
Phase Phase 1

Sponsor

AstraZeneca

1,285 total trials

What the Registry Record Tells You About NCT03616587

The ClinicalTrials.gov registry entry for NCT03616587 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 396 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with ER+ HER2- Advanced Breast Cancer appearing as the primary indexed condition, and to 3 interventions - of which AZD9833 is the first listed.

NCT03616587 reports 17 study locations spanning 6 distinct geographic areas - top geographies include Other, Colorado, Florida.

Frequently Asked Questions

What is clinical trial NCT03616587 about?

NCT03616587 is a clinical study titled "Study of AZD9833 Alone or in Combination in Women With Advanced Breast Cancer.". A Phase 1 Dose Escalation and Expansion Study of AZD9833 Alone or in Combination in Women with ER Positive, HER2 Negative Advanced Breast Cancer (SERENA-1)

What is the current status of trial NCT03616587?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 396 participants. The study started on 2018-10-11. Estimated completion is 2027-06-24.

What conditions does trial NCT03616587 study?

This clinical trial studies the following conditions: ER+ HER2- Advanced Breast Cancer.

What interventions are being tested in trial NCT03616587?

The interventions under investigation include: AZD9833 (DRUG), AZD9833 with palbociclib (DRUG), AZD9833 with everolimus (DRUG).

Who is sponsoring clinical trial NCT03616587?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03616587 being conducted?

This trial has 17 study locations across Colorado, Florida, Pennsylvania, Tennessee, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for ER+ HER2- Advanced Breast Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.