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NCT03612960 · ClinicalTrials.gov registry record · NA
Measuring Neuroadaptations in Response to Very Low Nicotine Content Cigarettes
A NA study, sponsored by Milton S. Hershey Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 34
- Enrollment target
NCT03612960: Completed NA study, sponsored by Milton S. Hershey Medical Center.
NCT03612960 is a NA study that has completed, run by Milton S. Hershey Medical Center. The registered enrollment target is 34 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03612960, a NA study, has completed, sponsored by Milton S. Hershey Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 34 participants
- Enrollment target
Study Summary
The overall goal of this study is to determine if switching to very low nicotine content cigarettes changes the function of brain circuitry involved in incentive salience and executive control among dependent smokers.
Primary Outcome
Change from baseline to 6-weeks post-intervention in percentage of BOLD signal during hard vs. no choice conditions on a monetary delay discounting task in a left-sided cortical brain region encompassing the central opercular and dorsolateral prefrontal cortices.
Interventions
- DRUG Very low nicotine content cigarettes
- DRUG Normal nicotine content cigarettes
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2020-02-20 |
| Est. Completion | 2023-06-23 |
| Phase | NA |
What the finished NCT03612960 record still lists
NCT03612960 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Very low nicotine content cigarettes is the first listed.
NCT03612960 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03612960 about?
NCT03612960 is a clinical study titled "Measuring Neuroadaptations in Response to Very Low Nicotine Content Cigarettes". The overall goal of this study is to determine if switching to very low nicotine content cigarettes changes the function of brain circuitry involved in incentive salience and executive control among dependent smokers.
What is the current status of trial NCT03612960?
This trial is currently completed. It is a NA study. The enrollment target is 34 participants. The study started on 2020-02-20. Estimated completion is 2023-06-23.
What interventions are being tested in trial NCT03612960?
The interventions under investigation include: Very low nicotine content cigarettes (DRUG), Normal nicotine content cigarettes (DRUG).
Who is sponsoring clinical trial NCT03612960?
This trial is sponsored by Milton S. Hershey Medical Center, which has 396 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03612960's enrollment target sits among peer trials
34 1570th of 2000 higher than 427 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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